TFInfer: a tool for probabilistic inference of transcription factor activities


SUMMARY: TFInfer is a novel open access, standalone tool for genome-wide inference of transcription factor activities from gene expression data. Based on an earlier MATLAB version, the software has now been extended in a number of ways. It has been significantly optimised in terms of performance, and it was given novel functionality, by allowing the user to model both time series and data from multiple independent conditions. With a full documentation and intuitive graphical user interface, together with an in-built data base of yeast and Escherichia coli transcription factors, the software does not require any mathematical or computational expertise to be used effectively. AVAILABILITY: CONTACT: SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.


PubMed ID: 20739311

Projects: SUMO

Journal: Bioinformatics


Date Published: 24th Aug 2010

Authors: H M Shahzad Asif, Matthew Rolfe, Jeff Green, Neil D Lawrence, Magnus Rattray, Guido Sanguinetti

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Views: 3631

Created: 21st Oct 2010 at 19:55

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