New surveyor tools for charting microbial metabolic maps
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BiBTeXThe computational reconstruction and analysis of cellular models of microbial metabolism is one of the great success stories of systems biology. The extent and quality of metabolic network reconstructions is, however, limited by the current state of biochemical knowledge. Can experimental high-throughput data be used to improve and expand network reconstructions to include unexplored areas of metabolism? Recent advances in experimental technology and analytical methods bring this aim an important step closer to realization. Data integration will play a particularly important part in exploiting the new experimental opportunities.
SEEK ID: https://fairdomhub.org/publications/11
PubMed ID: 18026122
Projects: STREAM
Publication type: Not specified
Journal: Nat. Rev. Microbiol.
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Date Published: 21st Nov 2007
Registered Mode: Not specified
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Created: 26th May 2010 at 14:43
Last updated: 8th Dec 2022 at 17:25
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Projects: STREAM, SilicoTryp
Institutions: University of Groningen
I am currently Professor of Systems Biology at the University of Manchester. My research interests focus on the development of innovative computational approaches for post-genomic systems biology, statistical methods for high-throughput biological experimentation and the dynamic modelling of cellular systems. This work is highly interdisciplinary and usually involves close collaboration with experimental biologists and clinicians. A recurrently theme is the study of complex cellular networks at ...
Projects: STREAM
Institutions: University of Warwick
Systems Biologist specialising in data integration, high-throughput sequence analysis, and evolutionary and comparative analyses.
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
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