MicroRNAs are a recently discovered group of factors that control cell behaviour. There are thousands of microRNAs, but specific ones control the behaviour of cartilage cells and have key roles in osteoarthritis. Changing the level of a single microRNA can alter osteoarthritis, but we know that several microRNAs change during disease. The group has identified four microRNAs which have key roles in cartilage. This programme seeks:
to show that these microRNAs have a role in osteoarthritis in the
Public web page: http://dunhillmedical.org.uk/project/david-young-programme/
A joint NTNU and SINTEF project to establish a knowledge platform on DHA synthesis and lipid accumulation in the native DHA-producing thraustochytrids, and to develop these into high productivity omega-3 fatty acid producing cell factories.