Studies
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This study contains our single nuclei characterisation of whole hearts from Fzt.DU mice published in Cells.
Submitter: Markus Wolfien
Investigation: 1 hidden item
Predictions made using the core model for combinatorial perturbations to the model simulating combined effects from OE, KO mutants, perturbations and time series concentrations.
Submitter: Niels Zondervan
Investigation: Modelling of M. pneumoniae metabolism
Assays: 40 samples, OE mutants of glycolysis and pyruvate metabolism enzymes com...
Internal metabolites concentrations for time series data (not pulse experiments) and for mutant OE, KO mutants and perturbations External metabolite concentrations for time series data (not pulse experiments) and for mutant OE, KO mutants and perturbations Mutant (OE, KO, perturbation) metabolite measurements
Training of the core model, parameter estimation using Evolutionary Programming using metabolomics, proteomics and some flux data. The core model contains reactions in glycolysis, pyruvate metabolism and ATPase
Validation of the core model of glycolysis, pyruvate metabolism and ATPase reaction using OE, KO mutant samples and perturbation samples
This section contains all the raw data and files required for each figures.
Submitter: Dorothee Houry
Investigation: 1 hidden item
Assays: FIGURE 2: Crystal structures of human NAMPT in complex with NA and PRPP,..., FIGURE 3: ATP is essential for NAMN formation by NAMPT, FIGURE 4: ATP indirectly stabilizes PRPP via pHis247., FIGURE 5: The deletion of the β1-β2 loop does not alter the geometry of ..., FIGURE 6: SAXS analysis of WT and Δ42-51 NAMPT.
Construction of a Genome scale constrained-based metabolic modeling of M. hyopneumonia
Submitter: Niels Zondervan
Investigation: Modelling of M. pneumoniae metabolism
Assays: Construction of a Genome Scale Metabolitic model of M. hyopneumoniae
Proteomics Average and SD data for time series data, 6h, 12h, 24h, 48h,72, 96h per protein
Submitter: Niels Zondervan
Investigation: Modelling of M. pneumoniae metabolism
Assays: Proteomics assay
Contains copy number per locus tag at different times of Growth between 0.25h and 96 hours. M. pneumoniae was grown in Batch, cells attached to the bottom of the flask (single cell layer), non stirred, non aerated.
Submitter: Niels Zondervan
Investigation: Modelling of M. pneumoniae metabolism
Assays: Transcriptomics assay of M. pneumoniae at diferent times of growth