Data files

Results of default run of Schrödinger QikProp (Schrödinger, LLC, New York, NY, Schrödinger Release 2015-4, 2015, QikProp v4.6.) for newly synthesized compounds of the merged series (5a-5f). QikProp in silico predicts various physico-chemical compound properties and advanced descriptors related to administration, distribution, metabolism, excretion and toxicity of the compounds.

Results of default run of Schrödinger QikProp (Schrödinger, LLC, New York, NY, Schrödinger Release 2015-4, 2015, QikProp v4.6.) for the entire in silico pteridine library. QikProp in silico predicts various physico-chemical compound properties and advanced descriptors related to administration, distribution, metabolism, excretion and toxicity of the compounds.

Results of default run of Schrödinger QikProp (Schrödinger, LLC, New York, NY, Schrödinger Release 2015-4, 2015, QikProp v4.6.) for reference pteridines (series 1) and newly synthesized N10-, PABA and tail-modified pteridines (series 2, 3 and 4). QikProp in silico predicts various physico-chemical compound properties and advanced descriptors related to administration, distribution, metabolism, excretion and toxicity of the compounds.

Gene expression data of various genes from cod liver.

Gene expression data of genes involved in steroidogenic pathways, measured in cod ovaries.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original MRI Data, Bruker folder structure but Exam folders use "display name", i.e. 2/ becomes E002_Anatomy_Light_T2_E2/.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Original Bruker MRI data (fid, 2dseq, dicom) but with renamed exam folders based on the display name.

Analysis to determine fold change in mRNA for selected targets (COX-2, IL1B, IL8, 5-LOX, TLR4, iNOS, TNFa)

Analysis to determine fold change in mRNA for selected targets (COX-2, IL1B, IL8, 5-LOX, TLR4, iNOS, TNFa)