Quarto document with R code for transcriptome profiling, including input files, result figures and rendered PDF Version 1
SEEK ID: https://fairdomhub.org/data_files/7938?version=1
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analyses_tlr8_inhibition.zip
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Created: 24th Jul 2025 at 23:12
Last updated: 29th Sep 2025 at 12:25
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Version 1 (earliest) Created 24th Jul 2025 at 23:12 by Inken Wohlers
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Projects: Group Data Science, Group Microbial Interface Biology, Core Facility Fluorescence Cytometry, Targeting the immunoproteasome: Analyzing the biological effects of specific versus pan inhibition, Macrophage and neutrophil redox proteome in infection with Mycobacterium tuberculosis, Methylation differences during respiratory infection, Lipid droplet formation and dynamics in murine macrophages, Implementation of Nanopore Sequencing for Detection of Treatment Induced Transcriptomic and Epitranscriptomic Changes in Leukaemic Tumour Models, Revisiting mutational resistance to ampicillin and cefotaxime in Haemophilus influenzae, OMICS of vascular smooth muscle cells under oxidative stress, Systems genetics of lung health and asthma (GWAS, PGS, QTL), Archaean stimulation of human primary PBMCs and PBMCs monocytes, iMED-RISK: Improvement of risk stratification in infant medulloblastoma using integrated models of clinical, histopathological and molecular data
Institutions: Forschungszentrum Borstel
https://orcid.org/0000-0003-4004-0464
The FZB is the lung research center of the Leibniz Association and is therefore committed to the motto “theoria cum praxi”.
The FZB sees its scientific and socio-political task in basic, disease- and patient-oriented lung research and training in this field. The field of research includes chronic inflammatory diseases of the lung of infectious and non-infectious environmental and behavioral origin. Research focuses on tuberculosis, infections with non-tuberculous mycobacteria and other bacterial ...
Projects: Group Data Science, Group Microbial Interface Biology, Core Facility Fluorescence Cytometry, Targeting the immunoproteasome: Analyzing the biological effects of specific versus pan inhibition, Macrophage and neutrophil redox proteome in infection with Mycobacterium tuberculosis, Methylation differences during respiratory infection, Lipid droplet formation and dynamics in murine macrophages, OMICS of vascular smooth muscle cells under oxidative stress, Systems genetics of lung health and asthma (GWAS, PGS, QTL), Archaean stimulation of human primary PBMCs and PBMCs monocytes, iMED-RISK: Improvement of risk stratification in infant medulloblastoma using integrated models of clinical, histopathological and molecular data
Web page: https://fz-borstel.de
The conditions are Control: Control (no stimulation, no TLR8 inhibition) Inhib: TLR8 inhibition Msm: Methanobrevibacter smithii stimulation Mst: Methanosphaera stadtmanae stimulation Msm_Inhib: Methanobrevibacter smithii stimulation and TLR8 inhibition Mst_Inhib: Methanosphaera stadtmanae stimulation and TLR8 inhibition
Submitter: Inken Wohlers
Studies: Differential expression, Transcriptome profiling
Assays: Comparison of all conditions, Expression profiling with heatmaps and PCA
Submitter: Inken Wohlers
Investigation: Illumina RNA sequencing of archaean stimulated ...
Submitter: Inken Wohlers
Biological problem addressed: Model Analysis Type
Investigation: Illumina RNA sequencing of archaean stimulated ...
Study: Transcriptome profiling
