Pancreatic-Fibrosis logic-based model
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We constructed a logic-based model to unravel mechanisms underlying pancreatic cancer and fibrosis. Model was calibrated with expression data and simulated for stimulus response and perturbation analysis to identify disease markers. Disease markers predicted by the model are validated through patient data using KM survival plot (which stratify patient into short and long survival) and box plot (expression level of the markers in normal vs. pancreatic patients). In vitro validations of the model are in progress by our experimental partners.


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DOI: 10.15490/fairdomhub.1.datafile.4211.1

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Khan, F. (2021). Pancreatic-Fibrosis logic-based model [Data set]. FAIRDOMHub.

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Created: 13th Aug 2021 at 16:48

Last updated: 26th Aug 2021 at 08:55

Last used: 15th May 2022 at 17:37

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Version 1 Created 13th Aug 2021 at 16:48 by Faiz Khan

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