FAIRDOMHub

45 items tagged with 'Pharmacokinetics'.

Projects: HUMET Startup, COMBINE Multicellular Modelling, COVID-19 Disease Map, VHP project

Institutions: University Maastricht

https://orcid.org/0000-0002-5301-3142

Expertise: Systems Biology, Bioinformatics, interoperability, Data analysis, Data Integration, Toxicology, Nutrition, Transcriptomics, Pharmacokinetics, Microarray analysis

Tools: wikipathways, pathvisio, bridgedb

Raju Prasad Sharma

Projects: Service to URV Tarragona, Spain with respect to their Safety Assessment of Endocrine Disrupting Chemicals model (Active NOW), EraCoBiotech 2 nd call proposal preparation, SNAPPER: Synergistic Neurotoxicology APP for Environmental Regulation

Institutions: VU University Amsterdam, Universitat Rovira i Virgili

https://orcid.org/0000-0001-9103-9127

Expertise: PBPK modeling, Pharmacology, Pharmacokinetics, Mechanistic Modelling

Tools: R, Berkeley Madonna, Copasi, Cell designer

Digitized pharmacokinetics data (Spigset1999a)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Spigset1999a Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Spigset1999a), PNG (Spigset1999a)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 14:00

Digitized pharmacokinetics data (Jeppesen1996)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Jeppesen1996 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Jeppesen1996), PNG (Jeppesen1996)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 14:00

Digitized pharmacokinetics data (Oh2012)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Oh2012 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Oh2012), PNG (Oh2012)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 14:00

Digitized pharmacokinetics data (Healy1991)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Healy1991 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Healy1991), PNG (Healy1991)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 14:00

Digitized pharmacokinetics data (Akinyinka2000)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Akinyinka2000 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Akinyinka2000), PNG (Akinyinka2000)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 14:00

Digitized pharmacokinetics data (Kakuda2014)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Kakuda2014 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Kakuda2014), PNG (Kakuda2014)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 14:00

Digitized pharmacokinetics data (Haller2002)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Haller2002 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Haller2002), PNG (Haller2002)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 14:00

Digitized pharmacokinetics data (Amchin1999)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Amchin1999 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Amchin1999), PNG (Amchin1999)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 13:59

Digitized pharmacokinetics data (Kaplan1997)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Kaplan1997 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Kaplan1997), PNG (Kaplan1997)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 13:59

Digitized pharmacokinetics data (Blanchard1983a)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Blanchard1983a Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Blanchard1983a), PNG (Blanchard1983a)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 13:59

Digitized pharmacokinetics data (Tanaka2014)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Tanaka2014 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Tanaka2014), PNG (Tanaka2014)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 13:59

Digitized pharmacokinetics data (Perera2011)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Perera2011 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Perera2011), PNG (Perera2011)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 13:59

Digitized pharmacokinetics data (Magnusson2008)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Magnusson2008 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Magnusson2008), PNG (Magnusson2008)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 13:59

Digitized pharmacokinetics data (Hetzler1990)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Data digitized from publication.

Hetzler1990 Description

Submitter: Matthias König

Assay type:

Technology type:

Investigation: MM-PLF: Multiscale modeling for personalized li...

Study: PKDB Caffeine Study

Organisms: Homo sapiens

SOPs: No SOPs

Data files: CSV (Hetzler1990), PNG (Hetzler1990)

Snapshots: No snapshots

Created: 19th Jul 2019 at 13:57, Last updated: 19th Jul 2019 at 13:59

PNG (Spigset1999a)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Spigset1999a)

Download

Created: 19th Jul 2019 at 14:00, Last updated: 19th Jul 2019 at 14:00

PNG (Jeppesen1996)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Jeppesen1996)

Download

Created: 19th Jul 2019 at 14:00, Last updated: 19th Jul 2019 at 14:00

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Oh2012)

Download

Created: 19th Jul 2019 at 14:00, Last updated: 19th Jul 2019 at 14:00

PNG (Healy1991)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Healy1991)

Download

Created: 19th Jul 2019 at 14:00, Last updated: 19th Jul 2019 at 14:00

PNG (Akinyinka2000)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Akinyinka2000)

Download

Created: 19th Jul 2019 at 14:00, Last updated: 19th Jul 2019 at 14:00

PNG (Kakuda2014)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Kakuda2014)

Download

Created: 19th Jul 2019 at 14:00, Last updated: 19th Jul 2019 at 14:00

PNG (Haller2002)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Haller2002)

Download

Created: 19th Jul 2019 at 14:00, Last updated: 19th Jul 2019 at 14:00

PNG (Amchin1999)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Amchin1999)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 14:00

PNG (Kaplan1997)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Kaplan1997)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

PNG (Blanchard1983a)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Blanchard1983a)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

PNG (Tanaka2014)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Tanaka2014)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

PNG (Perera2011)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Perera2011)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

PNG (Magnusson2008)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Magnusson2008)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

PNG (Hetzler1990)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Hetzler1990)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

CSV (Spigset1999a)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Spigset1999a)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

CSV (Jeppesen1996)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Jeppesen1996)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Oh2012)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

CSV (Healy1991)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Healy1991)

Download

Created: 19th Jul 2019 at 13:59, Last updated: 19th Jul 2019 at 13:59

CSV (Akinyinka2000)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Akinyinka2000)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:59

CSV (Kakuda2014)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Kakuda2014)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

CSV (Haller2002)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Haller2002)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

CSV (Amchin1999)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Amchin1999)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

CSV (Kaplan1997)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Kaplan1997)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

CSV (Blanchard1983a)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Blanchard1983a)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

CSV (Tanaka2014)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Tanaka2014)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

CSV (Perera2011)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Perera2011)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

CSV (Magnusson2008)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Magnusson2008)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

CSV (Hetzler1990)

Multi-Scale Models for Personalized Liver Function Tests (LiSyM-MM-PLF)

Digitized pharmacokinetics data.

Creator: Matthias König

Submitter: Matthias König

Investigations: MM-PLF: Multiscale modeling for personalized li...

Studies: PKDB Caffeine Study

Assays: Digitized pharmacokinetics data (Hetzler1990)

Download

Created: 19th Jul 2019 at 13:58, Last updated: 19th Jul 2019 at 13:58

Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism

SteaPKMod

(Show All)

Abstract (Expand)

Abstract Little is known about the impact of morphological disorders in distinct zones on metabolic zonation. It was described recently that periportal fibrosis did affect the expression of CYP proteins, …

Authors: Mohamed Albadry, Sebastian Höpfl, Nadia Ehteshamzad, Matthias König, Michael Böttcher, Jasna Neumann, Amelie Lupp, Olaf Dirsch, Nicole Radde, Bruno Christ, Madlen Christ, Lars Ole Schwen, Hendrik Laue, Robert Klopfleisch, Uta Dahmen

Date Published: 1st Dec 2022

Publication Type: Journal

DOI: 10.1038/s41598-022-26483-6

Citation: Sci Rep 12(1),21825

Created: 17th Dec 2022 at 20:34, Last updated: 17th Dec 2022 at 20:40

(v.1.16.0)

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