Figure 3A: Model calibration with experimental data of JAK2-STAT5 signaling obtained by different experimental techniques.

For all experiments, primary CFU-E cells were starved and stimulated with 5 U/ml Epo. At the indicated time points, samples were subjected to quantitative immunoblotting. Experimental data (black circles) with estimated standard errors and trajectories of the best fit (solid lines) are represented. Mass spectrometry data represent replicates of four independent experiments.

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Created: 3rd Mar 2016 at 10:52

Last updated: 3rd Mar 2016 at 11:06

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