JAK2/STAT5 model Version 1
Simulate Model on Copasi
Simulate Model on JWSSEEK ID: https://fairdomhub.org/models/185?version=1
1 item is associated with this Model:-
msb201150-sup-0002.xml (XML document - 28.5 KB)
Organism: Not specified
Model type: Ordinary differential equations (ODE)
Model format: SBML
Execution or visualisation environment: JWS Online
Model image: No image specified
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Creators and Submitter
Views: 4637 Downloads: 128 Runs: 3
Created: 3rd Mar 2016 at 09:47
Last updated: 3rd Mar 2016 at 10:06
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Version History
Version 1 (earliest) Created 3rd Mar 2016 at 09:47 by Dawie van Niekerk
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Projects: PSYSMO, MOSES, SysMO DB, SysMO-LAB, SulfoSys, SulfoSys - Biotec, Whole body modelling of glucose metabolism in malaria patients, FAIRDOM, Molecular Systems Biology, COMBINE Multicellular Modelling, HOTSOLUTE, Steroid biosynthesis, Yeast glycolytic oscillations, Computational pathway design for biotechnological applications, SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers, Project Coordination, WP 3: Drug release kinetics study, Glucose metabolism in cancer cell lines
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester, University of Stellenbosch, University of Manchester - Department of Computer Science, Stellenbosch University
https://orcid.org/0000-0003-2633-0537
This programme is used to store published data files that are not available in other FAIRDOM projects. We specifically store information for journals that we collaborate with for technical curation of mathematical models. These files are used in COMBINE archives to reproduce journal figures.
Projects: Molecular Systems Biology
Web page: Not specified
The Molecular Systems Biology project holds information for reproducing simulation figures in the journal. This can include experimental data files, model files and manuscript information.
Programme: Journals
Public web page: http://msb.embopress.org
Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range
For all experiments, primary CFU-E cells were starved and stimulated with 5 U/ml Epo. At the indicated time points, samples were subjected to quantitative immunoblotting. Experimental data (black circles) with estimated standard errors and trajectories of the best fit (solid lines) are represented. Mass spectrometry data represent replicates of four independent experiments.
SED-ML simulation: https://jjj.bio.vu.nl/models/experiments/bachmann2011/simulate
Submitter: Dawie van Niekerk
Biological problem addressed: Model Analysis Type
Investigation: Bachmann et al (2011) Molecular Systems Biology...
