Assays

Assay for the isolation of intact Plasmodium falciparum trophozoites from infected red blood cells and the preparation of a cell free extract that can be used for kinetic analyses.

Submitter: Dawie van Niekerk

Assay type: Experimental Assay Type

Technology type: Technology Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

SOPs: No SOPs

Data files: No Data files

Snapshots: No snapshots

Created: 15th Aug 2014 at 13:02, Last updated: 8th Nov 2017 at 14:21

Inhibition of glucose transport

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model analysis

Organisms: Plasmodium falciparum

Models: GLCtr kinetic model incorporating inhibition

SOPs: No SOPs

Data files: GLCtr inhibition kinetic data

Snapshots: No snapshots

Created: 2nd Jul 2015 at 10:24, Last updated: 8th Nov 2017 at 14:21

Inhibition of lactate flux

Whole body modelling of glucose metabolism in malaria patients

Inhibition of lactate flux due to glucose transport inhibitor

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model analysis

Organisms: Plasmodium falciparum

Models: Kinetic model for steady state (penkler1), Kinetic model incorporating glucose transport i..., Validation of lactate flux inhibition by glucos...

SOPs: No SOPs

Data files: Lactate flux inhibition data

Snapshots: No snapshots

Created: 2nd Jul 2015 at 10:33, Last updated: 8th Nov 2017 at 14:21

Supply-demand analysis

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model analysis

Organisms: Plasmodium falciparum

Models: Kinetic model for steady state (penkler1), Supply demand analysis on penkler1 model

SOPs: No SOPs

Data files: No Data files

Snapshots: No snapshots

Created: 10th Jul 2015 at 10:28, Last updated: 8th Nov 2017 at 14:21

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of HK.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: HK Kinetic model

SOPs: HK Kinetic characterisation

Data files: HK Kinetic data

Snapshots: Snapshot 1

Created: 8th Aug 2014 at 13:30, Last updated: 8th Nov 2017 at 14:21

PGI

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of PGI.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: PGI Kinetic model

SOPs: PGI Kinetic characterisation

Data files: PGI Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:27, Last updated: 8th Nov 2017 at 14:21

PFK

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of PFK.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: PFK Kinetic model

SOPs: PFK Kinetic characterisation

Data files: PFK Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:29, Last updated: 8th Nov 2017 at 14:21

ALD

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of ALD.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: ALD Kinetic model

SOPs: ALD Kinetic characterisation

Data files: ALD Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:30, Last updated: 8th Nov 2017 at 14:21

TPI

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of TPI.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: TPI Kinetic model

SOPs: TPI Kinetic characterisation

Data files: TPI Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:31, Last updated: 8th Nov 2017 at 14:21

G3PDH

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of G3PDH.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: G3PDH Kinetic model

SOPs: G3PDH Kinetic characterisation

Data files: G3PDH Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:32, Last updated: 8th Nov 2017 at 14:21

GAPDH

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of GAPDH.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: GAPDH Kinetic model

SOPs: GAPDH Kinetic characterisation

Data files: GAPDH Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:33, Last updated: 8th Nov 2017 at 14:21

PGK

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of PGK.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: PGK Kinetic model

SOPs: PGK Kinetic characterisation

Data files: PGK Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:34, Last updated: 8th Nov 2017 at 14:21

PGM

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of PGM.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: PGM Kinetic model

SOPs: PGM Kinetic characterisation

Data files: PGM Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:35, Last updated: 8th Nov 2017 at 14:21

ENO

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of ENO.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: ENO Kinetic model

SOPs: ENO Kinetic characterisation

Data files: ENO Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:41, Last updated: 8th Nov 2017 at 14:21

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation en mathematical modelling of PK.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: PK Kinetic model

SOPs: PK Kinetic characterisation

Data files: PK Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:41, Last updated: 8th Nov 2017 at 14:21

LDH

Whole body modelling of glucose metabolism in malaria patients

Kinetic characterisation and mathematical modelling of LDH.

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: LDH Kinetic model

SOPs: LDH Kinetic characterisation

Data files: LDH Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:42, Last updated: 8th Nov 2017 at 14:21

GLC incubation

Whole body modelling of glucose metabolism in malaria patients

SED-ML simulation: https://jjj.bio.vu.nl/models/experiments/penkler2aa_experiment-user/simulate

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model validation

Organisms: No organisms

Models: Kinetic model for incubation (penkler2)

SOPs: Validation experiments

Data files: 5mM GLC runout data.

Snapshots: No snapshots

Created: 11th Aug 2014 at 07:52, Last updated: 8th Nov 2017 at 14:21

GLCtr

Whole body modelling of glucose metabolism in malaria patients

No description specified

Submitter: Dawie van Niekerk

Biological problem addressed: Model Analysis Type

Investigation: Glucose metabolism in Plasmodium falciparum tro...

Study: Model construction

Organisms: No organisms

Models: GLCtr Kinetic model

SOPs: No SOPs

Data files: GLCtr Kinetic data

Snapshots: No snapshots

Created: 11th Aug 2014 at 09:18, Last updated: 8th Nov 2017 at 14:21

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