Projects: The Hedgehog Signalling Pathway (LiSyM-JGMMS)
Institutions: Universität Leipzig - Medizinische Fakultät - Institut für Biochemie
Expertise: Liver Zonation, morhogenic signalling, metabolism
Tools: qPCR, immunohistochemistry, FACS, ChiP
Projects: SulfoSys - Biotec, ICYSB 2015 - International Practical Course in Systems Biology
Institutions: Otto-von-Guericke University Magdeburg, University of Gothenburg
https://orcid.org/0000-0001-6971-2530Expertise: Signalling networks, dynamics of biological networks., Databases, Data analysis, Systems Biology, Model selection, Identifiability, Cellular Senescence, Cell Cycle, Dynamic Systems, Image processing, Image analysis, Parameter estimation
Tools: ODE, FACS, Model selection, Fluorescence and confocal microscopy, Identifiability analysis, Parameter estimation
My group investigates dynamic regulation and control mechanisms of cellular signal transduction networks by a combination of theoretical, experimental and computational methods. We seek to make sense of our biological data with the help of mathematical models, which ideally enable us to make valid predictions for new experiments, thereby generating novel biological insights.
Projects: BaCell-SysMO
Institutions: University of Groningen
Expertise: Gram positive bacteria (Bacillus, Lactococcus, Streptococcus), competence, sporulation, germination, antimicrobial peptides, phenotypic heterogeneity, bistability, C- and N- metabolism, gene regulation, stress responses, pathogens, virulence factors, metal ion homeostasis, protein secretion
Tools: Biochemistry, Genetics, Molecular Biology, Bioinformatics, Genomics, Transcriptomics, time lapse microscopy, FACS, genomic array footprinting
Group leader Molecular Genetics