To investigate phenol degradation in Saccharolobus solfataricus transcriptome and metabolome analyses were performed with cells grown on phenol as sole carbon source. Cells grown on D-glucose served as reference. Metabolic modelling was used to compare efficiency of phenol utilization in terms of oxygen demand and energy yield with the reference condition.
SEEK ID: https://fairdomhub.org/studies/770
Phenol degradation in Saccharolobus solfataricus P2
Projects: SulfoSys - Biotec
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Meina Neumann-Schaal, Jörn Kalinowski
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Created: 23rd Jul 2020 at 13:46
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Public web page: http://www.sulfosys.com/
Organisms: Sulfolobus solfataricus
Present in many industrial effluents and as intermediate of lignin degradation, phenol is a widespread pollutant causing serious environmental problems, due to its toxicity to animals and humans. Removal of phenol from the environment by bacteria has been studied extensively over the past decades, but only little is known about phenol biodegradation in hostile environments. We combined metabolomics and transcriptomics together with metabolic modelling to elucidate the organism’s response to growth ...
Submitter: Jacqueline Wolf
Studies: Comparison of S. solfataricus P2 grown on phenol vs D-glucose
Assays: Metabolome analysis: phenol vs D-glucose, RNA Sequencing: phenol vs D-glucose
Snapshots: No snapshots
Submitter: Jacqueline Wolf
Assay type: Experimental Assay Type
Technology type: Gas Chromatography
Investigation: Phenol degradation in Saccharolobus solfataricu...
Organisms: Sulfolobus solfataricus
SOPs: No SOPs
Data files: Metabolome analysis phenol vs glucose
Snapshots: No snapshots
Submitter: Jacqueline Wolf
Assay type: Experimental Assay Type
Technology type: Rna-seq
Investigation: Phenol degradation in Saccharolobus solfataricu...
Organisms: Sulfolobus solfataricus
SOPs: No SOPs
Data files: Transcriptome analysis phenol vs glucose
Snapshots: No snapshots
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Investigations: Phenol degradation in Saccharolobus solfataricu...
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