To investigate phenol degradation in Saccharolobus solfataricus transcriptome and metabolome analyses were performed with cells grown on phenol as sole carbon source. Cells grown on D-glucose served as reference. Metabolic modelling was used to compare efficiency of phenol utilization in terms of oxygen demand and energy yield with the reference condition.
SEEK ID: https://fairdomhub.org/studies/770
Phenol degradation in Saccharolobus solfataricus P2
Projects: SulfoSys - Biotec
Study position:
Export PNG
Creators
Additional credit
Meina Neumann-Schaal, Jörn Kalinowski
Submitter
Views: 738
Created: 23rd Jul 2020 at 13:46
This item has not yet been tagged.
Related items
Projects: SulfoSys - Biotec
Institutions: University Bielefeld
https://orcid.org/0000-0002-3394-1304Projects: SulfoSys, PSYSMO, SulfoSys - Biotec, EbN1 Systems Biology
Institutions: University of Braunschweig
Projects: SulfoSys, SulfoSys - Biotec, HOTSOLUTE, Computational pathway design for biotechnological applications, SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers
Institutions: University Duisburg-Essen, Universitity Duisburg-Essen
https://orcid.org/0000-0002-9905-541XHead of the group of Molecular Enzyme Technology and Biochemistry (Faculty of Chemistry) at the University of Duisburg-Essen. My research interest is on archaeal physiology with a special focuss on the central carbohydrate metabolism of (hyper)thermophilic Archaea and its regulation. The aim is to gain a systems level understanding by the combination of modern highthrouput analyses with classical biochemistry and molecular biology. Archaea possess many novel enzymes and pathways and our aim is ...
e:Bio - Innovations Competition Systems Biology
Projects: SulfoSys - Biotec, SBEpo - Systems Biology of Erythropoietin
Web page: http://www.fona.de/en/14276
Within the e:Bio - Innovationswettbewerb Systembiologie (Federal Ministry of Education and Research (BMBF)), the SulfoSYSBIOTECH consortium (10 partners), aim to unravel the complexity and regulation of the carbon metabolic network of the thermoacidophilic archaeon Sulfolobus solfataricus (optimal growth at 80°C and pH 3) in order to provide new catalysts ‘extremozymes’ for utilization in White Biotechnology.
Based on the available S. solfataricus genome scale metabolic model (Ulas et al., 2012) ...
Programme: e:Bio
Public web page: http://www.sulfosys.com/
Organisms: Sulfolobus solfataricus
Present in many industrial effluents and as intermediate of lignin degradation, phenol is a widespread pollutant causing serious environmental problems, due to its toxicity to animals and humans. Removal of phenol from the environment by bacteria has been studied extensively over the past decades, but only little is known about phenol biodegradation in hostile environments. We combined metabolomics and transcriptomics together with metabolic modelling to elucidate the organism’s response to growth ...
Submitter: Jacqueline Wolf
Studies: Comparison of S. solfataricus P2 grown on phenol vs D-glucose
Assays: Metabolome analysis: phenol vs D-glucose, RNA Sequencing: phenol vs D-glucose
Snapshots: No snapshots
Submitter: Jacqueline Wolf
Assay type: Experimental Assay Type
Technology type: Gas Chromatography
Investigation: Phenol degradation in Saccharolobus solfataricu...
Organisms: Sulfolobus solfataricus
SOPs: No SOPs
Data files: Metabolome analysis phenol vs glucose
Snapshots: No snapshots
Submitter: Jacqueline Wolf
Assay type: Experimental Assay Type
Technology type: Rna-seq
Investigation: Phenol degradation in Saccharolobus solfataricu...
Organisms: Sulfolobus solfataricus
SOPs: No SOPs
Data files: Transcriptome analysis phenol vs glucose
Snapshots: No snapshots
Creators: Andreas Albersmeier, Jörn Kalinowski
Submitter: Jacqueline Wolf
Investigations: Phenol degradation in Saccharolobus solfataricu...
Creator: Jacqueline Wolf
Submitter: Jacqueline Wolf
Investigations: Phenol degradation in Saccharolobus solfataricu...