SEEK ID: https://fairdomhub.org/studies/59
The effect of pH upon the metabolic shift in Clostridium acetobutylicum in continuous culture.
Projects: COSMIC
Study position:
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Created: 8th Nov 2010 at 15:36
Last updated: 22nd Nov 2011 at 19:12
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Projects: COSMIC
Institutions: University of Rostock
Expertise: Microbiology, Biotechnology
Tools: Transcriptomics, Fermentation, Proteomics (2D-PAGE), Gaschromatographic analysis
PhD University of Rostock, Germany Institute of Biological Sciences Division of Microbiology Albert-Einstein-Str. 3 18051 Rostock
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
Systems Biology of Clostridium acetobutylicum - a possible answer to dwindling crude oil reserves
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=54
Organisms: Clostridium acetobutylicum
Submitter: Christina Döring
Studies: Effect of pH on the metabolome, Effect of pH on the proteome, Effect of pH upon the transcriptome, Identification of clusters of co-regulated and anti-regulated genes, Modelling the effect of pH on the metabolic shift
Assays: Comparison of the proteome between pH 5.7 (acidogenesis) and pH 4.5 (sol..., Comparison of the transcriptome between pH 5.7 (acidogenesis) and pH 4.5..., Comparison of the transcriptome between pH 5.8 (acidogenesis) and pH 4.5..., Identification of dynamically similar transcript profiles, Steady state study of the effect of gene regulation on yields of end-pro..., Study of the end products of the acidogenesis and solventogenesis pathways, Time-dependent simulations
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Measurements of acetone, butanol, acetate, butyrate and ethanol taken during dynamic shift (pH 5.8, 5.5, 5.3, 5.1, 4.9, 4.7, 4.5) and at steady state (pH 5.7, 5.5, 5.3, 5.1, 4.9, 4.7, 4.5).
Submitter: Sara Jabbari
Assay type: Metabolomics
Technology type: Technology Type
Investigation: The effect of pH upon the metabolic shift in Cl...
Organisms: Clostridium acetobutylicum : ATCC824 (wild-type / wild-type)
SOPs: No SOPs
Data files: End products of Clostridium acetobutylicum grow..., End products of Clostridium acetobutylicum grow...
Snapshots: No snapshots
Monitoring of end products ethanol, acetone, butanol, acetate and butyrate during master fermentation of Clostridium acetobutylicum at the steady state pH values 5.5, 5.3, 5.1, 4.9 and 4.7.
Creator: Holger Janssen
Submitter: Holger Janssen
Investigations: The effect of pH upon the metabolic shift in Cl...
Studies: Effect of pH on the metabolome
Monitoring of end products in mM of ethanol, acetone, butanol, acetate and butyrate during master fermentation of Clostridium acetobutylicum at the steady state pH values 5.7 (acidogenesis) and 4.5 (solventogenesis).
Creator: Holger Janssen
Submitter: Holger Janssen
Investigations: The effect of pH upon the metabolic shift in Cl...
Studies: Effect of pH on the metabolome
Abstract (Expand)
Authors: , , , Birgit Voigt, Michael Hecker, ,
Date Published: 1st Aug 2010
Publication Type: Not specified
DOI: 10.1007/s00253-010-2741-x
Citation: