Construction and characterization of three lactate dehydrogenase-negative Enterococcus faecalis V583 mutants


The roles of the two ldh genes of Enterococcus faecalis were studied using knockout mutants. Deletion of ldh-1 causes a metabolic shift from homolactic fermentation to ethanol, formate, and acetoin production, with a high level of formate production even under aerobic conditions. Ldh-2 plays only a minor role in lactate production.


PubMed ID: 19465534

Projects: SysMO-LAB

Journal: Appl. Environ. Microbiol.


Date Published: 22nd May 2009

Authors: Maria Jonsson, Zhian Saleihan, Ingolf Nes, Helge Holo

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Views: 1518

Created: 8th Jul 2010 at 19:04

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