Projects

What is a Project?
15 Projects found

Cyanobacteria are the only prokaryotes performing oxygenic photosynthesis. Theyhad and have tremendous influence on the biogeochemical cycles on Earth. Recently,cyanobacteria are increasingly investigated as cell factories for a sustainableeconomy. Despite their global, environmental and rising economic importance, ourknowledge on the regulation of their primary metabolism is fragmented.Cyanobacteria switch between photoautotrophic and heterotrophic modes ofmetabolism during day/night cycles or ...

Programme: DFG founded projects

Public web page: https://gepris.dfg.de/gepris/projekt/397695561

Start date: 1st Sep 2018

Hypoglycaemia and lactic acidosis are key diagnostics for poor chances of survival in malaria patients. In this project we aim to test to what extent the metabolic activity of Plasmodium falciparum contributes to a changed glucose metabolism in malaria patients. The approach is to start with detailed bottom up models for the parasite and then merge these with more coarse grained models at the whole body level.

No description specified

Programme: M-era.Net 3D4D2

Public web page: Not specified

Start date: 9th Aug 2021

End date: 8th Aug 2024

LEADER: StU (prof. B. Klumperman)

PARTNERS: StU & SU


OBJECTIVES:

• Optimization of antimalarial drug encapsulation for fast release.

• Development of transmission blocking drug encapsulation for slow release.


DELIVERABLES:

**07.2022 D ...

Programme: M-era.Net 3D4D2

Public web page: Not specified

Start date: 1st Jul 2021

End date: 1st Jan 2024

LEADER: prof. L-M. Birkholtz

PARTNERS: UP & WITS & SU & StU


OBJECTIVES:

• Evaluation of the ability of the novel polymer-drug systems to kill the transmissible gametocytes.

• Validation using treatment of anopheline mosquitoes in a membrane feeding assay.


...

Programme: M-era.Net 3D4D2

Public web page: Not specified

Start date: 1st Jul 2021

End date: 30th Jun 2024

LEADER: UL (prof. J.C. Simon)

PARTNERS: UL & IPF & SU & StU


OBJECTIVES:

• Validation of biocompatibility of the drug delivery systems with the skin.

• Testing of the drug delivery into and through the skin.


DELIVERABLES ...

Programme: M-era.Net 3D4D2

Public web page: Not specified

Start date: 1st Jul 2021

End date: 30th Jun 2024

LEADER: IPF (prof. A. Lederer)

PARTNERS: IPF & StU


OBJECTIVES:

• Determination of stability, degradation and drug release kinetics.

• Mathematical modelling of response to treatments of infectious diseases.


DELIVERABLES

10.2022 M 3.1 ...

Programme: M-era.Net 3D4D2

Public web page: Not specified

Start date: 1st Jul 2021

End date: 30th Jun 2024

Background- Thermophilic organisms are composed of both bacterial and archaeal species. The enzymes isolated from these species and from other extreme habitats are more robust to temperature, organic solvents and proteolysis. They often have unique substrate specificities and originate from novel metabolic pathways. Thermophiles as well as their stable enzymes (‘thermozymes’) are receiving increased attention for biotechnological applications.

The proposed project will establish thermophilic in ...

No description specified

Programme: Testing 1, 2, 3

Public web page: Not specified

No description specified

Programme: FAIR Biocatalysis

Public web page: Not specified

No description specified

Programme: FAIR Biocatalysis

Public web page: Not specified

No description specified

Programme: FAIR Biocatalysis

Public web page: Not specified

The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that:

  • facilitates and maximises the potential for data exchange between SysMO research groups;
  • maximises the ‘shelf life’ and ...

Programme: SysMO

Public web page: http://www.sysmo-db.org/

Within the e:Bio - Innovationswettbewerb Systembiologie (Federal Ministry of Education and Research (BMBF)), the SulfoSYSBIOTECH consortium (10 partners), aim to unravel the complexity and regulation of the carbon metabolic network of the thermoacidophilic archaeon Sulfolobus solfataricus (optimal growth at 80°C and pH 3) in order to provide new catalysts ‘extremozymes’ for utilization in White Biotechnology.

Based on the available S. solfataricus genome scale metabolic model (Ulas et al., 2012) ...

Programme: e:Bio

Public web page: http://www.sulfosys.com/

Comparative Systems Biology: Lactic Acid Bacteria

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