SEEK ID: https://fairdomhub.org/people/386
Location: United Kingdom
ORCID: Not specified
Joined: 11th Jul 2011
Expertise: Mathematical modelling
Tools: Computational and theoretical biology, ODE, Partial differential equations
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SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
Systems Biology of Clostridium acetobutylicum - a possible answer to dwindling crude oil reserves
Public web page: http://www.sysmo.net/index.php?index=54
Organisms: Clostridium acetobutylicum
This model assumes a phenotypic switch between an acid- and solvent-forming population caused by the changing pH levels. The two phenotypes differ in their transcriptomic, proteomic, and ,thus, their metabolomic profile. Because the growth rates of these phenotypes depends on the extracellular pH, the initiation of the pH-shift results in a significant decline of the acidogenic population. Simultaneously, the solvent-forming population rises and establishes an new steady state.
The model is build ...
Creators: Thomas Millat, Graeme Thorn, Olaf Wolkenhauer, John King
Submitter: Thomas Millat
Model type: Ordinary differential equations (ODE)
Model format: Matlab package
Organism: Clostridium acetobutylicum
Investigations: No Investigations
Studies: No Studies
Assays: No Assays
Creator: Graeme Thorn
Submitter: Sebastian Curth