Morpheus model of spatio-temporal liver zonation from Wnt-Hh crosstalk
Version 1

Download View content

Spatio-temporal liver zonation in mouse and human with Wnt-Hh crosstalk and transport are modeled using coupled partial differential equations. The model file is in MorpheusML format and can be opened in the free, open-source multicellular modeling software Morpheus (https://morpheus.gitlab.io). In Morpheus, the model will simulate the time course (movie) of dynamic liver zonation for a 2D cross-section of several liver lobules, showing the patterns of Wnt ligands, intracellular Wnt signaling, IHH, SHH, GLI3. The final state of this spatio-temporal simulation reproduces the control condition in Figure 5B of the publication (Kolbe et al., 2019).

SEEK ID: https://fairdomhub.org/models/759?version=1

1 item (and an image) are associated with this Model:
  • Spatio-temporal-model-of-liver-zonation-MorpheusML.xml (XML document - 6.23 KB) Download

Organism: Mus musculus

Model type: Partial differential equations (PDE)

Model format: Not specified

Execution or visualisation environment: Not specified

Model image: (Click on the image to zoom) (Original)

Help
help Creators and Submitter
Creators
Submitter
Activity

Views: 309   Downloads: 14

Created: 27th Nov 2020 at 17:38

Last updated: 27th Nov 2020 at 17:54

Last used: 24th Oct 2021 at 21:41

help Tags

Version History

Version 1 Created 27th Nov 2020 at 17:38 by Lutz Brusch

No revision comments

Related items

Powered by
(v.1.11.2)
Copyright © 2008 - 2021 The University of Manchester and HITS gGmbH

By continuing to use this site you agree to the use of cookies