Full title: Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human Date: December 24, 2019 Author: michael.kuecken@tu-dresden.de and lutz.brusch@tu-dresden.de Software: Morpheus (open-source), download from https://morpheus.gitlab.io Reference: This model is described in the peer-reviewed publication "Mutual Zonated Interactions of Wnt and Hh Signaling Are Orchestrating the Metabolism of the Adult Liver in Mice and Human" by E. Kolbe, S. Aleithe, C. Rennert, L. Spormann, F. Ott, D. Meierhofer, R. Gajowski, C. Stöpel, S. Hoehme, M. Kücken, L. Brusch, M. Seifert, W. von Schoenfels, C. Schafmayer, M. Brosch, U. Hofmann, G. Damm, D. Seehofer, J. Hampe, R. Gebhardt, M. Matz-Soja. Cell Reports 29, 4553, 2019. https://doi.org/10.1016/j.celrep.2019.11.104
Liver zonation
1 0.001-k1*w + cvein b*(w-a)*(1/(1+k2*h)-b) k3*c-k4*w*h-h b*c*c-k5*i k6*i+k7*h-k8*g