Kinetic model of Escherichia coli's electron transport chain (ETC) coupled to a simplified growth model
Version 2

The model describes the electron transport chain (ETC) of Escherichia coli by ordinary differential equations. Also a simplified growth model based on an abstract reducing potential describing the balance of electron donor (glucose) and electron acceptors is coupled to the ETC. The model should reproduce and predict the regulation of the described system for different oxygen availability within the aerobiosis scale (glucose limited continuous culture<=>chemostat). Therefore oxygen is changed slowly over time (linear increase) and the simulated variables can be considered as steady-states for single fixed oxygen concentrations (anaerobic=> microaerobic=> aerobic) in the inflowing gas. Time=20000 corresponds to 100% aerobiosis (end of model validity). Different glucose concentrations Glcin and dilution rates Dil can be simulated by changing the corresponding parameters and the parameter JO2in100 for the maximal oxygen flow.


1 item is associated with this Model:
  • EcoliETC2.xml (SBML and XML document - 81.9 KB)

Organism: Escherichia coli

Model type: Ordinary differential equations (ODE)

Model format: SBML

Execution or visualisation environment: JWS Online

Model image: No image specified

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Views: 3055   Downloads: 2

Created: 30th May 2011 at 10:09

Last used: 7th Jul 2020 at 16:23

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