Programmes
What is a Programme?
The Snoep Lab’s core research efforts are in Computational Systems Biology; a combined experimental, modeling and theoretical approach to quantitatively understand the functional behavior of Biological Systems resulting from the characteristics of their components. Our main focus is on metabolism, of human pathogens such as Plasmodium falciparum, Mycobacterium tuberculosis, but also of breast cancer cell lines, and on modelling disease states such as glucose homeostatis in type 2 diabetes, and ...
Projects: Whole body modelling of glucose metabolism in malaria patients, Steroid biosynthesis, Yeast glycolytic oscillations, Computational pathway design for biotechnological applications, Glucose metabolism in cancer cell lines
Web page: http://www.sun.ac.za/english/faculty/science/biochemistry/research/snoep-group
Projects: Unshackling Membrane Protein Research: New Amphiphilic Copolymers for Extraction of Stable, Active Membrane Proteins, WP1 - Structure-activity relationships of amphiphilic copolymers, WP2.1 - Mono-chain-end functional amphiphilic copolymers, WP2.2 - Hetero di-chain-end functional amphiphilic copolymers, WP2.4 - Block copolymers for tethering to surfaces, WP2.3 - Meta-stable amphiphilic copolymers, WP2.5 - Fusion of SMALPs, WP2.6 - SMALPs for photosynthetic research, WP3 - Scalability of polymer production process, WP4 - Community engagement and technical advice
Web page: Not specified
Projects: WP 1: Biodegradable and responsive polymer matrix, WP 2: Antimalarial drug encapsulation, WP 3: Drug release kinetics study, WP 4: Evaluation of drug activity against multiple life cycle stages of malaria parasites, WP 5: Intradermal 3D drug device administration, Project Coordination
Web page: Not specified
This is the exchange platform of the COMBINE network.
COMBINE is an initiative to coordinate the development of various community standards and formats for computational models: BioPax, CellML, NeuroML, Synthetic Biology Open Language (SBOL), Systems Biology Graphical Notation (SBGN), Systems Biology Markup Language (SBML), Simulation Experiment Description Markup Language (SED-ML).
Projects: COMBINE Multicellular Modelling, ModeleXchange initiative
Web page: http://co.mbine.org
This programme is used to store published data files that are not available in other FAIRDOM projects. We specifically store information for journals that we collaborate with for technical curation of mathematical models. These files are used in COMBINE archives to reproduce journal figures.
Projects: Molecular Systems Biology
Web page: Not specified
