CEL-250716SHE-3
samples-publish_250716_CEL.xlsx
DC_Blebb
https://fairdomhub.org/sops/836
Homo sapiens
Vivek Shenoy
Primary human monocyte-derived dendritic cells (DCs)
Not specified
CEL-250716SHE-1
Experimental
Blebbistatin
Sigma-Aldrich
20
uM
Creators and SubmitterViews: 0
Created: 16th Jul 2025 at 17:44
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Projects: Hi-IMPAcTB, MIT SRP, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC), Shoulders Lab
Institutions: Massachusetts Institute of Technology
Projects: MIT SRP, Hi-IMPAcTB, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC), Shoulders Lab
Web page: https://nextseek.mit.edu/
Understanding the spectrum of complex metastatic processes is important to the development of a comprehensive and cohesive understanding of cancer metastasis. The Metastasis Research Network (MetNet) supports collaborative, multidisciplinary projects that focus on several themes of the metastatic process and use integrative systems-level approaches.
MetNet is advancing the understanding of metastasis as a non-linear, dynamic, and emergent process, as well as revealing mechanistic insights of early ...
Programme: NExtSEEK
Public web page: Not specified
Submitter: Charles Demurjian
Studies: Chemo-mechanical diffusion waves explain collective dynamics of immune c..., Chromatin conformation, gene transcription, and nucleosome remodeling as..., Confined cell migration along extracellular matrix space in vivo, Impact of fibrinogen, fibrin thrombi and thrombin on cancer cell extrava..., Patient-specific vascularized tumor model: Blocking monocyte recruitment..., Personalized Vascularized Models of Breast Cancer Desmoplasia Reveal Bio..., Polyploidy of MDA-MB-231 cells drives increased extravasation with enhan..., Utilizing convolutional neural networks for discriminating cancer and st...
Assays: All Metadata, All Metadata, All Metadata, All Metadata, All Metadata, Cancer Cell Extravasation Analysis - Data Linked, Cancer Cell Extravasation Analysis - Data Linked, Cell Culture - Metadata, Cell Culture - Metadata, Cell Culture Imaging - Data Linked, Cell Culture Imaging Analysis - Data Linked, Cell Culture and Tumor Spheroid Creation - Metadata, Cell Culture and Tumor Spheroid Creation - Metadata, Cell Imaging - Data Linked, Chromatin Sequencing Analysis - Data Linked, Clot Modeling Analysis - Data Linked, Convolutional Neural Network - Data Linked, Dendritic Cell Preparation - Metadata, Device Creation - Metadata, Device Creation - Metadata, Device Imaging - Data Linked, Device Imaging - Data Linked, Device Imaging - Data Linked, Device Imaging - Metadata, Flow Cytometry - Data Linked, Flow Cytometry - Data Linked, Flow Cytometry Analysis - Data Linked, Flow Cytometry Analysis - Data Linked, Fluorescence-Activated Cell Sorting - Data Linked, Gene Expression Analysis - Data Linked, Imaging Analysis - Data Attached, Imaging Analysis - Data Linked, Imaging Analysis - Data Linked, Imaging Analysis - Data Linked, Intravital Microscopy, Library Creation - Metadata, Library Prep - Metadata, Live Cell Imaging - Data Linked, Microfluidic Device Creation - Metadata, Microfluidic Device Creation - Metadata, Microfluidic Device Imaging - Data Linked, Microvascular Network Formation - Metadata, Migration Assay Analysis - Data Linked, Modeling - Data Linked, Modeling - Data Linked, Permeability Analysis - Data Linked, RNA Extraction - Metadata, Real-time RT-PCR - Data Linked, Short Read Sequencing - Data Linked, Short Read Sequencing - Data Linked, Tumoroid Formation - Metadata
Ze Gong, Koen van den Dries, Rodrigo A. Migueles-RamÃrez, Paul W. Wiseman, Alessandra Cambi & Vivek B. Shenoy
DOI: https://doi.org/10.1038/s41467-023-38598-z
Abstract: Immune cells, such as macrophages and dendritic cells, can utilize podosomes, mechanosensitive actin-rich protrusions, to generate forces, migrate, and patrol for foreign antigens. Individual podosomes probe their microenvironment through periodic protrusion and retraction cycles (height ...
Submitter: Charles Demurjian
Investigation: MetNet
Assays: All Metadata, Dendritic Cell Preparation - Metadata, Imaging Analysis - Data Linked, Live Cell Imaging - Data Linked, Modeling - Data Linked
Submitter: Charles Demurjian
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MetNet
Submitter: Charles Demurjian
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MetNet
Batch sample publishing
Creator: Charles Demurjian
Submitter: Charles Demurjian
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