Physiological proteomics and stress/starvation responses in Bacillus subtilis and Staphylococcus aureus
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BiBTeXGel-based proteomics is a useful approach for visualizing the responses of bacteria to stress and starvation stimuli. In order to face stress/starvation, bacteria have developed very complicated gene expression networks. A proteomic view of stress/starvation responses, however, is only a starting point which should promote follow-up studies aimed at the comprehensive description of single regulons, their signal transduction pathways on the one hand, and their adaptive functions on the other, and finally their integration into complex gene expression networks. This "road map of physiological proteomics" will be demonstrated for the general stress regulon controlled by sigma(B) in Bacillus subtilis and the oxygen starvation response with Rex as a master regulator in Staphylococcus aureus.
SEEK ID: https://fairdomhub.org/publications/86
PubMed ID: 19403106
Projects: BaCell-SysMO
Publication type: Not specified
Journal: Res. Microbiol.
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Date Published: 20th Feb 2009
Registered Mode: Not specified
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Created: 5th Oct 2010 at 08:23
Last updated: 8th Dec 2022 at 17:26
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By training I am a molecular microbiologist with a particular interest in bacterial stress adaptation reactions. Since the early 90ies we have used functional genomics technologies, particularly proteomics, to investigate the response of Bacillus subtilis to environmental challenges. I am currently Head of the Functional Genomics Department of the Interfaculty Institute of Genetics and Functional Genomics at the Ernst-Moritz-Arndt-University Greifswald. Within the Department we are applying ...
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
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