Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-<i>Trypanosoma brucei</i> Agents

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SEEK ID: https://fairdomhub.org/publications/772

Projects: WG1 - Compound libraries coordination and integration of compound design, WG2 - Integration of early phase studies and low environmental impact ac..., WG3 - Coordination of in vitro-to-in vivo translation of OneHealth leads..., WG4 - Integration of R&D process-environmental studies and translation i...

Publication type: Journal Article

Journal: ACS Infectious Diseases

Book Title: ACS Infectious Diseases

Publisher: American Chemical Society (ACS)

Citation: ACS Infect. Dis. 10(8):2755-2774.

Date Published: 2nd Jul 2024

Registered Mode: by DOI

Authors: Valeria Francesconi, Marco Rizzo, Cecilia Pozzi, Lorenzo Tagliazucchi, Claude U. Konchie Simo, Giulia Saporito, Giacomo Landi, Stefano Mangani, Anna Carbone, Silvia Schenone, Nuno Santarém, Joana Tavares, Anabela Cordeiro-da-Silva, Maria Paola Costi, Michele Tonelli

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Ulrike Wittig

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Francesconi, V., Rizzo, M., Pozzi, C., Tagliazucchi, L., Konchie Simo, C. U., Saporito, G., Landi, G., Mangani, S., Carbone, A., Schenone, S., Santarém, N., Tavares, J., Cordeiro-da-Silva, A., Costi, M. P., & Tonelli, M. (2024). Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-Trypanosoma brucei Agents. In ACS Infectious Diseases (Vol. 10, Issue 8, pp. 2755–2774). American Chemical Society (ACS). https://doi.org/10.1021/acsinfecdis.4c00113

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Created: 14th Jul 2026 at 08:08

Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-<i>Trypanosoma brucei</i> Agents

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