Version 1

Download View content

The image file represents the activation of sigB in response to glucose starvation. It was drawn alongside the model 'sigb-response_starvation_shakeflask'. Biomass catalyses the conversion of glucose to biomass, while a low glucose concentration will negatively affect cell viability (inverted shown in the figure, where Glc inhibits cell death). W (RsbW) can form dimers with sigB (B) and dimers and trimers with V (RsbV)(WV, WV2) and is able to phosphorylate V to VP. A high glucose concentration inhibits the dephosphorylation of VP. sigB dependent transcription alongside sigA (A) dependent transcription stays constant. Upon glucose starvation dephosphorylation of VP increases V which performs partner switch with sigB on W. sigB is released to start the transcription of stress response genes.


Filename: sigb_full.gif  Download

Format: GIF image

Size: 25.4 KB

help Creators and Submitter

Views: 1842   Downloads: 47

Created: 26th Oct 2009 at 15:48

Last used: 26th Jun 2022 at 02:52

help Tags

This item has not yet been tagged.

help Attributions


Version History

Version 1 Created 26th Oct 2009 at 15:48 by Ulf Liebal

No revision comments

Powered by
Copyright © 2008 - 2022 The University of Manchester and HITS gGmbH

By continuing to use this site you agree to the use of cookies