This profile is created to handle PoLiMeR data only - mainly the materials from Anne-Claire M.F. Martines PhD thesis (temporary solution)
SEEK ID: https://fairdomhub.org/people/1509
ORCID: Not specified
Joined: 27th Feb 2020
Expertise: metabolism, Liver, fatty acid, Metabolic Models
Tools: experimental tools, Modeling
- Projects (1)
- Institutions (1)
- Investigations (0+2)
- Studies (0+4)
- Assays (0+1)
- Data files (1)
- SOPs (0+1)
- Publications (2)
- Samples (0+1)
PoLiMeR is funded through the EU Marie Skłodowska-Curie Innovative Training Network (ITN), which drives scientific excellence and innovation. ITNs bring together universities, research institutes, industry and clinical partners from across the world to train researchers to doctorate level.
Metabolic diseases are a burden on the European population and health care system. It is increasingly recognised that individual differences with respect to history, lifestyle, and genetic make-up affect disease ...
Programme: This Project is not associated with a Programme
Public web page: http://polimer-itn.eu/
Organisms: Homo sapiens, Mus musculus, Rattus norvegicus
Transcriptome analysis suggests a compensatory role of the cofactors coenzyme A and NAD+ in medium-chain acyl-CoA dehydrogenase knockout mice. During fasting, mitochondrial fatty-acid β-oxidation (mFAO) is essential for the generation of glucose by the liver. Children with a loss-of-function deficiency in the mFAO enzyme medium-chain acyl-Coenzyme A dehydrogenase (MCAD) are at serious risk of life-threatening low blood glucose levels during fasting in combination with intercurrent disease. However, ...
Creators: PoLiMeR_user Martines_data, Terry G.J. Derks, Barbara Bakker, Martines AMF
Submitter: PoLiMeR_user Martines_data
Investigations: 1 hidden item
Studies: 1 hidden item
Assays: 1 hidden item
Authors: F. Abegaz, A. M. F. Martines, M. A. Vieira-Lara, M. Rios-Morales, D. J. Reijngoud, E. C. Wit, B. M. Bakker
Date Published: 13th Aug 2021
Publication Type: Journal
PubMed ID: 34383741
Citation: PLoS Comput Biol. 2021 Aug 12;17(8):e1009259. doi: 10.1371/journal.pcbi.1009259. eCollection 2021 Aug.
Authors: H. Herrema, T. G. Derks, T. H. van Dijk, V. W. Bloks, A. Gerding, R. Havinga, U. J. Tietge, M. Muller, G. P. Smit, F. Kuipers, D. J. Reijngoud
Date Published: 7th May 2008
Publication Type: Not specified
PubMed ID: 18459129
Citation: Hepatology. 2008 Jun;47(6):1894-904. doi: 10.1002/hep.22284.