Morpheus model of spatio-temporal YAP/Hippo pathway activation during liver regeneration
Version 1

For the spatio-temporal dynamics of bile transport, bile canalicular dilation, mechanical stimulation and transduction of YAP signaling during liver regeneration see the open access publication and its appendix: Meyer et al. (2020) Bile canaliculi remodeling activates YAP via the actin cytoskeleton during liver regeneration. Molecular Systems Biology 16:e8985.

The model format is MorpheusML that can readily be loaded and run in the free and open source software Morpheus: This simulation yields a movie of the spatio-temporal dynamics of total and nuclear YAP in a file of cells.


1 item (and an image) are associated with this Model:
  • YAP_Signaling_Liver_Regeneration.xml (XML document - 11.2 KB) Download

Organism: Mus musculus

Model type: Ordinary differential equations (ODE)

Model format: Not specified

Execution or visualisation environment: Not specified

Model image: (Click on the image to zoom) (Original)

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Views: 1037   Downloads: 23

Created: 27th Nov 2020 at 18:04

Last updated: 27th Nov 2020 at 18:04

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Version 1 (earliest) Created 27th Nov 2020 at 18:04 by Lutz Brusch

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