Morpheus model of spatio-temporal YAP/Hippo pathway activation during liver regeneration
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For the spatio-temporal dynamics of bile transport, bile canalicular dilation, mechanical stimulation and transduction of YAP signaling during liver regeneration see the open access publication and its appendix: Meyer et al. (2020) Bile canaliculi remodeling activates YAP via the actin cytoskeleton during liver regeneration. Molecular Systems Biology 16:e8985. https://doi.org/10.15252/msb.20198985

The model format is MorpheusML that can readily be loaded and run in the free and open source software Morpheus: https://morpheus.gitlab.io This simulation yields a movie of the spatio-temporal dynamics of total and nuclear YAP in a file of cells.

SEEK ID: https://fairdomhub.org/models/760?version=1

1 item (and an image) are associated with this Model:
  • YAP_Signaling_Liver_Regeneration.xml (XML document - 11.2 KB) Download

Organism: Mus musculus

Model type: Ordinary differential equations (ODE)

Model format: Not specified

Execution or visualisation environment: Not specified

Model image: (Click on the image to zoom) (Original)

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Views: 291   Downloads: 12

Created: 27th Nov 2020 at 18:04

Last updated: 27th Nov 2020 at 18:04

Last used: 25th Oct 2021 at 08:13

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Version 1 Created 27th Nov 2020 at 18:04 by Lutz Brusch

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