For the spatio-temporal dynamics of bile transport, bile canalicular dilation, mechanical stimulation and transduction of YAP signaling during liver regeneration see the open access publication and its appendix: Meyer et al. (2020) Bile canaliculi remodeling activates YAP via the actin cytoskeleton during liver regeneration. Molecular Systems Biology 16:e8985. https://doi.org/10.15252/msb.20198985
The model format is MorpheusML that can readily be loaded and run in the free and open source software Morpheus: https://morpheus.gitlab.io This simulation yields a movie of the spatio-temporal dynamics of total and nuclear YAP in a file of cells.
Organism: Mus musculus
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Execution or visualisation environment: Not specified
Model image: (Click on the image to zoom) (Original)