Metabolic model of Sulfolobus solfataricus Version 2
Simulate Model on Copasi
Simulate Model on JWSMetabolic model of Sulfolobus solfataricus P2 in the SBML (sbml) and metano (txt, sce, fba) format. Scenarios are specific for growth on D-glucose or caseinhydrolysate as sole carbon source.
SEEK ID: https://fairdomhub.org/models/231?version=2
7 items are associated with this Model:-
Sulfolobus-solfataricus_model.txt (Plain text document - 190 KB)
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Sulfolobus-solfataricus_Caseinhydrolysate.fba (Binary file - 145 KB)
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Sulfolobus-solfataricus_Caseinhydrolysate.sce (Binary file - 30.7 KB)
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Sulfolobus-solfataricus_D-glucose.fba (Binary file - 145 KB)
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Sulfolobus-solfataricus_D-glucose.sce (Binary file - 30.7 KB)
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Sulfolobus-solfataricus_Caseinhydrolysate.sbml (XML document - 1.17 MB)
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Sulfolobus-solfataricus_D-glucose.sbml (XML document - 1.17 MB)
Organism: Sulfolobus solfataricus
Model type: Metabolic network
Model format: SBML
Execution or visualisation environment: Not specified
Model image: No image specified
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Creators and SubmitterViews: 2891 Downloads: 234 Runs: 0
Created: 12th Oct 2016 at 09:03
Last updated: 24th Apr 2017 at 16:00
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Version History
Version 2 (latest) Created 7th Nov 2016 at 12:44 by Helge Stark
*Changed 'casamino_acids' to 'caseinhydrolysate'
Related items
Projects: SulfoSys - Biotec
Institutions: University of Braunschweig
e:Bio - Innovations Competition Systems Biology
Projects: SulfoSys - Biotec, SBEpo - Systems Biology of Erythropoietin
Web page: http://www.fona.de/en/14276
Within the e:Bio - Innovationswettbewerb Systembiologie (Federal Ministry of Education and Research (BMBF)), the SulfoSYSBIOTECH consortium (10 partners), aim to unravel the complexity and regulation of the carbon metabolic network of the thermoacidophilic archaeon Sulfolobus solfataricus (optimal growth at 80°C and pH 3) in order to provide new catalysts ‘extremozymes’ for utilization in White Biotechnology.
Based on the available S. solfataricus genome scale metabolic model (Ulas et al., 2012) ...
Programme: e:Bio
Public web page: http://www.sulfosys.com/
Integrated systems biology approach including transcriptome, metabolome, proteome analyses and modelling to elucidate amino acid degradation in S. solfataricus P2.
Submitter: Jacqueline Wolf
Studies: Comparison of Sulfolobus solfataricus P2 grown on caseinhydrolysate and ...
Assays: Metabolic modelling of S. solfataricus during growth on casaminoacids, Metabolome analysis: Casaminoacids versus D-Glc, Proteome analysis: Casaminoacids versus D-Glc, RNA sequencing: Casaminoacids vs D-glc
To investigate amino acid degradation pathways in Sulfolobus solfataricus transcriptome, proteome and metabolome analyses were performed on cells grown on caseinhydrolysate as carbon source. Cells grown with glucose served as reference condition. Metabolic modelling was used to compare the efficiency of different degradation routes.
Submitter: Jacqueline Wolf
Investigation: Amino acid degradation in Sulfolobus solfataric...
Assays: Metabolic modelling of S. solfataricus during growth on casaminoacids, Metabolome analysis: Casaminoacids versus D-Glc, Proteome analysis: Casaminoacids versus D-Glc, RNA sequencing: Casaminoacids vs D-glc
Growth on D-glucose served as reference scenario
Submitter: Jacqueline Wolf
Biological problem addressed: Genome Scale
Investigation: Amino acid degradation in Sulfolobus solfataric...
Abstract (Expand)
Authors: J. Wolf, H. Stark, K. Fafenrot, A. Albersmeier, T. K. Pham, K. B. Muller, B. Meyer, L. Hoffmann, L. Shen, S. P. Albaum, T. Kouril, K. Schmidt-Hohagen, M. Neumann-Schaal, C. Brasen, J. Kalinowski, P. C. Wright, S. V. Albers, D. Schomburg, B. Siebers
Date Published: 10th Sep 2016
Publication Type: Not specified
