Creation of the KEGG based Reactome
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Created: 29th Nov 2012 at 11:11
Last updated: 29th Nov 2012 at 11:24
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Projects: COSMIC
Institutions: Beuth University of Applied Sciences Berlin
I am a biotechnologist with main focus on theoretical studies. Currently, I am working on the implementation of a parameter estimation algorithm on GPUs to reduce the computational burden of huge ODE systems. I am a PAL and I am looking forward to communication with other SYSMO members.
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
Systems Biology of Clostridium acetobutylicum - a possible answer to dwindling crude oil reserves
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=54
Organisms: Clostridium acetobutylicum
Automated model building using Taverna workflows from KEGG-Database
Submitter: Sebastian Curth
Studies: Automated Model Building, Reactome Analysis, Transcriptome Analysis
Assays: Example for model derivation from KEGG, Graph Analysis, Integration of data into the model, KEGG Data Mining
Snapshots: No snapshots
Using Taverna for mining and MATLAB for conversion into specific formats (cytoscape, SBTOOLBOX2)
Submitter: Sebastian Curth
Biological problem addressed: Model Analysis Type
Investigation: Modular Model Building
Study: Reactome Analysis
Organisms: Clostridium acetobutylicum : ATCC824 (wild-type / wild-type)
Models: No Models
SOPs: No SOPs
Data files: Network statistics of Reactome, Results of Reaction Mining, Taverna Workflow for Compound Annotation from KEGG, Taverna Workflow for Gene-Reaction-Substrate-Pr..., Visualisation of Reaction Networks in C. acetob...
Snapshots: No snapshots
Cytoscape based analysis and yED based representation of clostridial Reactomes
Submitter: Sebastian Curth
Biological problem addressed: Model Analysis Type
Investigation: Modular Model Building
Study: Reactome Analysis
Organisms: Clostridium acetobutylicum : ATCC824 (wild-type / wild-type)
Models: No Models
SOPs: No SOPs
Data files: Network statistics of Reactome, Visualisation of Reaction Networks in C. acetob...
Snapshots: No snapshots
Basic Graph statistics
RCM: Reaction-Compound Mapping, an edge between nodes means reaction contains metabolite MMM: Metabolite-Metabolite Mapping, an edge between nodes means these metabolites are reaction partners
_comp: entire network after removal of duplicated edges _del: taken from the entire network the largest connected subgraph after deletion of a set of nodes
betw: betweeness of nodes clos: closeness of nodes neigh: neighbours node_degree: number of edges per node path: shortest paths ...
Creator: Sebastian Curth
Submitter: Sebastian Curth
Investigations: Modular Model Building
Studies: Reactome Analysis
Assays: Graph Analysis, KEGG Data Mining
RCM: Reaction-Compound Mapping, an edge between nodes means reaction contains metabolite MMM: Metabolite-Metabolite Mapping, an edge between nodes means these metabolites are reaction partners
_comp: entire network after removal of duplicated edges _del: taken from the entire network the largest connected subgraph after deletion of a set of nodes _upload: entire network before removal of duplicated edges
X_depthY: subgraphs where X is a chosen central component and Y is the Yth of neighbour to ...
Creator: Sebastian Curth
Submitter: Sebastian Curth
Investigations: Modular Model Building
Studies: Reactome Analysis
Assays: Graph Analysis, KEGG Data Mining
Creator: Sebastian Curth
Submitter: Sebastian Curth
Out
Creator: Sebastian Curth
Submitter: Sebastian Curth
Columnwise datamatrix of reactions, gene identifiers, substrates and products. The direction of reactions is not given.
Creator: Sebastian Curth
Submitter: Sebastian Curth