In this study, we integrate COVID19 Disease Maps curated regulatory information in a macrophage logical model. This allows logical simulations of the effects of acute inflammation caused by the SARS-CoV-2 virus, both in general and in a cell-specific perspective. Moreover, understanding the regulatory network behavior of macrophages following infection opens new ways to test and predict drug and drug combination effects, as a first step towards the development of new treatments.
SEEK ID: https://fairdomhub.org/studies/828
Projects: COVID-19 Disease Map
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Projects: COVID-19 Disease Map

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Created: 5th Mar 2021 at 18:52

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