README file for s-core / s-core+ perl script

Version 1

The main objective of the ERANET proposal Systems Biology Applications - ERASysAPP (app = application = translational systems biology) is to promote multidimensional and complementary European systems biology projects, programmes and research initiatives on a number of selected research topics. Inter alia, ERASysAPP will initiate, execute and monitor a number of joint transnational calls on systems biology research projects with a particular focus on applications - or in other words so called ...

GMO free systems optimization of wine yeast for wine production by massive scale directed evolution

Gene co-epxression network analyses are common in the study of large scale biological data sets. In this study, we have developed a methodology for the comparison of pairs of co-expression networks using the s-core network peeling approach. We apply the methodology to gene-expression data for human and mouse.

s-core/ s-core+ network peeling is a methodology to identify cores of weighted complex networks.

We have developed a method for comparative analysis of pairs of complex networks based on gene co-expression analysis. We apply this modeling analysis to data set for gene expressions in multiple tissues of mus musculus and homo sapiens.