Using optical tweezers to position yeast cells in a microfluidic chamber, we were able to observe sustained oscillations in individual isolated cells. Using a detailed kinetic model for the cellular reactions, we simulated the heterogeneity in the response of the individual cells, assuming small differences in a single internal parameter. By operating at two different flow rates per experiment, we observe four of categories of cell behaviour. The present model (gustavsson4) predicts the steady-state behaviour observed in 25.7% of the cell population.
SEEK ID: https://fairdomhub.org/models/81?version=6
1 item is associated with this Model:Organism: Saccharomyces cerevisiae
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Execution or visualisation environment: JWS Online
Model image: No image specified

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Created: 23rd Jul 2012 at 23:17
Last updated: 23rd Oct 2012 at 13:42
Last used: 12th Aug 2022 at 17:29

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Version 6 (latest) Created 23rd Jul 2012 at 01:46 by Franco du Preez
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