Assays

Flow cytometry is employed to quantitatively measure cell surface and/or intracellular markers, enabling characterization of cell populations based on fluorescence intensity and light scatter properties. This assay utilizes a flow cytometer to analyze individual cells in suspension, providing multi-parametric data on cell phenotype, viability, activation state, or other biological attributes as defined by the experimental panel. Samples are processed, stained with fluorescently labeled antibodies ...

Library preparation converts extracted nucleic acids into sequencing-ready libraries. The process includes fragmentation, adapter ligation, and amplification to generate consistent input for sequencing instruments. Input: TIS, CEL, DNA or RNA sample Output: Indexed sequencing library suitable for sequencing assays.

Digitally barcoded Mtb matrix analysis processes barcode sequencing data from Mycobacterium tuberculosis infection experiments. It quantifies relative barcode abundance to track bacterial population dynamics. Input: Barcode sequencing files Output: Processed abundance matrix showing strain or barcode distribution.

This assay captures administrative and clinical metadata associated with patient study visits, serving as a structured data collection framework rather than a biological measurement assay. It records visit-level contextual information such as visit dates, timepoints, subject identifiers, clinical site details, and protocol-relevant annotations that are essential for linking experimental samples and assay results to their proper clinical context. This metadata layer ensures traceability and data ...

This assay captures metadata associated with tissue collection procedures, documenting critical provenance and contextual information for biological specimens obtained from study subjects. It records standardized parameters such as tissue type, anatomical source, collection method, preservation conditions, and relevant donor or sample identifiers to ensure traceability and reproducibility across downstream experimental workflows. This metadata serves as a foundational record linking collected ...

This assay quantifies gene expression at single-cell resolution by linking individual cell transcriptomic profiles to associated experimental or clinical data, enabling integrative analysis across multiple data modalities. Single-cell RNA sequencing (scRNA-seq) technology is employed to capture and measure the transcriptional activity of individual cells, generating high-dimensional expression matrices that are subsequently processed through quality control, normalization, and dimensionality ...

Short read sequencing is a high-throughput next-generation sequencing (NGS) approach used to determine the nucleotide sequence of DNA or RNA fragments, enabling detection of genetic variants, gene expression profiles, or genomic features depending on the library preparation strategy employed. This assay involves fragmentation of input nucleic acids, adapter ligation, and amplification prior to sequencing on short-read platforms (such as Illumina), generating millions of short sequence reads ...

DNA sequencing libraries are constructed from genomic DNA extracted from tissue samples through a series of enzymatic and physical processing steps, including DNA fragmentation, end-repair, adapter ligation, and amplification. This workflow prepares nucleic acid material for downstream high-throughput sequencing by converting extracted DNA into indexed, platform-compatible libraries. The resulting libraries enable comprehensive genomic or transcriptomic interrogation of tissue-derived specimens, ...

Flow cytometry is a laser-based, high-throughput single-cell analysis technique used to simultaneously measure multiple physical and fluorescent characteristics of cells or particles in suspension. This assay quantifies cell populations based on parameters such as cell size (forward scatter), granularity (side scatter), and fluorescence intensity of labeled surface or intracellular markers, enabling immunophenotyping, cell cycle analysis, viability assessment, and functional studies. Samples are ...

Antibody Dependent Functional Profiling* and Analysis Represents:

ADMP: Macrophage Phagocytosis

ADNP: Neutrophil Phagocytosis

ADDCP: Dendritic Cell Phagocytosis