Data repository to accompany the manuscript (TBC) on use of serum proteomics and robust machine learning to identify protein biomarkers for the discrimination of paediatric serum biomarker proteins.This repository contains key sample-level clinical metadata for the project, to work with the GitHub code: https://github.com/CBFLivUni/CNOSerumProteinsPublic.

Classic industrial chemical processes often rely on hazardous substances, consume energy, depend on non-recoverable materials, and produce toxic waste products. In contrast, enzymes catalyze the synthesis of molecules with remarkable selectivity under mild reaction conditions. This highlights the growing demand for affordable and sustainable production of small molecules with valuable activities, achievable through the integration of heterologous enzymes and substrates in biological synthetic ...

PhD project of Pauric Donnelly as part of the Talent4BBI programme

Cure-Q demo project to demonstrate how Fairdomseek works

Gene mutagenesis is a key technology in molecular biology and genetic engineering, enabling precise, controllable changes at specific DNA sites. It is essential for studying gene function, protein engineering, functional genomics, disease models, and industrial enzyme optimization. Creative Biogene leverages advanced platforms, mature strategies, and high-fidelity systems to provide efficient, accurate, and flexible one-stop gene mutagenesis solutions.

some Description

Chronic kidney disease (CKD) affects around 9% of the global population and is the 12th leading cause of death (GBD Chronic Kidney Disease Collaboration 2020). Diabetic kidney disease (DKD) is the most common form of CKD, responsible for nearly half of all end-stage renal disease (ESRD) cases (Samsu 2021). Despite its high burden, progress in developing effective therapies has been slow, largely due to limited understanding of the underlying molecular mechanisms.

DKD is driven by complex and ...

AIRC

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Produktion von Ethylacetat aus Molkerückständen mit Kluyveromyces marxianus und Produktgewinnung mittels Membranverfahren

MS-Proteomics and Lipidomics raw data associate with the present research paper

MS-Proteomics raw data repository

Test project

Komplexe, erweiterte Leberresektionen ((e)PHx) stellen ein hohes Risiko für ein postoperatives Leberversagen dar, insbesondere bei einer bereits bestehenden Lebererkrankung. Das Ziel von QuaLiPerF ist es, bisher unbekannte Wechselwirkungen zwischen den durch die Operation verursachten Veränderungen der Perfusion und der Stoffwechselfunktion aufzuklären. Wir werden einen systemmedizinischen Ansatz anwenden, um ein mehrskaliges Modell der Leberperfusion und -funktion zu erstellen, das die Vorhersage ...

A fundamental and enduring challenge for ecosystem managers developing risk and impact assessment tools is to predict the extent of impact that spilled oil can have on the immediate fish populations and on future generations. Modelling approaches are important tools for these assessments, but they currently suffer from two major shortcomings: 1) the failure to acknowledge that effects can be transferred through several generations and 2) the assumption that a small group of toxic compounds, ...

HubMOL is a Marie Skłodowska-Curie Actions Doctoral Network funded by Horizon Europe.

The hub molecules of life comprise a set of cofactors that are crucial for all cellular functions. They are well known for their central roles in both metabolism and signalling. Still, our limited knowledge of the crosstalk and the reciprocal connectivity between key metabolic and signal transduction pathways and the dynamic interplay of hub molecules is currently hampering their exploitation. Imbalances in hub ...

As a scientists-founded and scientists-driven leading biotechnological company, Creative Biogene focuses on developing high quality products and services, as well as proprietary technology to support the research in the field of basic life sciences research, biomedical development, industrial synthetic application and preclinical drug discovery.

This project provides datasets supporting the analysis of carbon partitioning and metabolite excretion in different Synechocystis sp. PCC 6803 strains. It includes intracellular and extracellular metabolite measurements, glycogen quantification, and sampling metadata, enabling investigation of carbon overflow and glycogen metabolism under different nitrogen conditions.

Research Training Group 2901 SYLOBIO

Systemic and local reactions in case of incompatibility to biomaterials for joint and skin lesions

Incompatibility to biomaterials and the body's response

Biomaterials serve as temporary or permanent replacements for tissue structures that are irreversibly damaged or functionally impaired. Possible incompatibility of biomaterials used for total joint replacements and dressings for chronic wounds is triggered by inflammatory reactions in the host tissue, ...

CBPP Research