Reporting on genes, transcription factors and metabolites Version 1
Summary 1.1 modifying TFinfer to model the TFs using ON/OFF switches (fast response model), 1.2 trying to infer metabolites effect using a joint gene-tf-metabolite model, 2 analysing aerbiosis data using a similar model, 3 clustering genes for extending the EC network to obtain better fits to the data (feedback loop).
SEEK ID: https://fairdomhub.org/presentations/79?version=1
Filename: sumo2mdb.pdf
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Created: 25th Jan 2013 at 11:16
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Version 1 (earliest) Created 25th Jan 2013 at 11:16 by Botond Cseke
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Projects: SUMO
Institutions: University of Edinburgh
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
"Systems Understanding of Microbial Oxygen responses" (SUMO) investigates how Escherichia coli senses oxygen, or the associated changes in oxidation/reduction balance, via the Fnr and ArcA proteins, how these systems interact with other regulatory systems, and how the redox response of an E. coli population is generated from the responses of single cells. There are five sub-projects to determine system properties and behaviour and three sub-projects to employ different and complementary modelling ...
Programme: SysMO
Public web page: http://www.sysmo.net/index.php?index=55
