SEEK ID: https://fairdomhub.org/people/2861
Location:
United States
ORCID: Not specified
Joined: 24th Jul 2026
Expertise: Not specified
Tools: Not specified
Roles
Project administrator
- MIT SRP
- Hi-IMPAcTB
- Cancer Systems Biology Consortium (CSBC)
- NExtSEEK Independent Projects
- Endometriosis
- MetNet
Asset housekeeper
- MIT SRP
- Hi-IMPAcTB
- Cancer Systems Biology Consortium (CSBC)
- NExtSEEK Independent Projects
- Endometriosis
- MetNet
Asset gatekeeper
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Related items
- Programmes (1)
- Projects (6)
- Institutions (1)
- Studies (1)
- Assays (12)
- SOPs (6+3)
- Publications (1)
- Sample types (0+9)
- Samples (222)
Projects: MIT SRP, Hi-IMPAcTB, MetNet, Endometriosis, Cancer Systems Biology Consortium (CSBC), Shoulders Lab, NExtSEEK Independent Projects
Web page: https://nextseek.mit.edu/
Understanding the spectrum of complex metastatic processes is important to the development of a comprehensive and cohesive understanding of cancer metastasis. The Metastasis Research Network (MetNet) supports collaborative, multidisciplinary projects that focus on several themes of the metastatic process and use integrative systems-level approaches.
MetNet is advancing the understanding of metastasis as a non-linear, dynamic, and emergent process, as well as revealing mechanistic insights of early ...
Programme: NExtSEEK
Public web page: Not specified
Organisms: Not specified
Endometriosis research done by the Griffith lab (MIT) and the Goods lab (Dartmouth)
Programme: NExtSEEK
Public web page: Not specified
Organisms: Not specified
Programme: NExtSEEK
Public web page: Not specified
Organisms: Not specified
ABSTRACT – OVERALL The primary focus of the MIT/DFCI Center for Systems Biology of Glioblastoma is to understand the intersections between neurons, immune cells, and tumor cells in this deadly tumor. The lack of response to immunotherapy strategies despite prominent infiltrates of immune cells in many GBM highlights the immuno- suppressive nature of the GBM microenvironment and the importance of more clearly understanding the dynamic interactions at the tumor/immune interface. Similarly, interactions ...
Programme: NExtSEEK
Public web page: Not specified
Organisms: Not specified
About
This project houses all the publicly available datasets generated by the Hi-IMPAcTB consortium over the course of its 7+ years.
What is Hi-IMPAcTB?
Hi-IMPAcTB is an ambitious endeavor bringing together a team of international, interdisciplinary researchers to improve our understanding of host-pathogen interactions in the context of tuberculosis (TB). Funded by a multi-center contract from the NIH, the long-term goal of the consortium is to enable principled vaccine design by improving ...
Programme: NExtSEEK
Public web page: https://grantome.com/grant/NIH/75N93019C00071-0-9999-1
Organisms: Mus musculus, Homo sapiens, Macaca fascicularis, Macaca mulatta
The MIT Superfund Research Program was created in 2017 to be responsive to communities who live near Superfund Sites. In particular, the MIT team leverages scientific research, community engagement, and educational experiences to support people who are concerned about hazardous chemicals in their environment.
Carcinogenic contaminants threaten the health of people living in the Mystic River Watershed (near the Olin, Industriplex, and Wells G&H Superfund sites) and members of Native American ...
Programme: NExtSEEK
Public web page: Not specified
Organisms: Not specified
ROR ID: Not specified
Department: Not specified
Country:
United States
City: Not specified
Web page: Not specified
Kay et al. 2026, DNA Repair 166 (2026) 103955 (DOI: 10.1016/j.dnarep.2026.103955; PMID: 42566817). A study of how sex and the Aag base-excision-repair gene modulate NDMA-induced liver damage, mutagenesis and tumourigenesis in mice.
Assays, data files and SOPs will be added as the deposit progresses. Reach out to Jenny Kay (kay@silentspring.org) with any questions.
Submitter: Juanita Pardo Sanchez
Investigation: MIT SRP
Assays: Chemical Challenge, Cleaved caspase-3 staining and analysis, Flow Cytometry, Flow Cytometry Analysis, GPT Assay, HistoPathology Analysis, Imaging, RaDR Image Machine Learning Analysis, Tissue Collection, Tissue Imaging, Tissue Sectioning, γH2AX staining and analysis
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: P.ENG-260831-V1_AnimalsAndNDMATreatment.docx
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: No SOPs
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: P.ENG-260831-V1_MicronucleusAssay.docx
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: P.ENG-260831-V1_MicronucleusAssay.docx
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: P.ENG-260831-V1_HistologicalAnalysis.docx
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: P.ENG-260831-V1_RaDRImaging.docx
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: P.ENG-260831-V1_GammaH2AXStaining.docx
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: P.ENG-260831-V1_CleavedCaspase3Staining.docx
Data files: No Data files
Snapshots: No snapshots
Submitter: Juanita Pardo Sanchez
Assay type: Experimental Assay Type
Technology type: Technology Type
Investigation: MIT SRP
Organisms: No organisms
SOPs: 1 hidden item
Data files: No Data files
Snapshots: No snapshots
Creators: None
Submitter: Juanita Pardo Sanchez
Investigations: MIT SRP
Studies: Sex and base excision repair as key susceptibil...
Assays: γH2AX staining and analysis
Creators: None
Submitter: Juanita Pardo Sanchez
Investigations: MIT SRP
Studies: Sex and base excision repair as key susceptibil...
Assays: Chemical Challenge
Creators: None
Submitter: Juanita Pardo Sanchez
Investigations: MIT SRP
Studies: Sex and base excision repair as key susceptibil...
Assays: HistoPathology Analysis
Creators: None
Submitter: Juanita Pardo Sanchez
Investigations: MIT SRP
Studies: Sex and base excision repair as key susceptibil...
Assays: Flow Cytometry, Flow Cytometry Analysis
Creators: None
Submitter: Juanita Pardo Sanchez
Investigations: MIT SRP
Creators: None
Submitter: Juanita Pardo Sanchez
Investigations: MIT SRP
Abstract (Expand)
Authors: J. E. Kay, J. J. Corrigan, L. B. Volk, A. L. Armijo, N. A. Owiti, L. J. Pribyl, I. S. Nazari, D. K. Torous, S. L. Avlasevich, R. G. Croy, D. N. Wadduwage, S. E. Carrasco, S. D. Dertinger, J. M. Essigmann, L. D. Samson, B. P. Engelward
Date Published: 4th Aug 2026
Publication Type: Journal Article
PubMed ID: 42566817
DOI: 10.1016/j.dnarep.2026.103955
Citation: DNA Repair (Amst). 2026 Aug 4;166:103955. doi: 10.1016/j.dnarep.2026.103955.
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