Studies
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Submitter: Andrew Millar
Investigation: Absolute units for proteins in Arabidopsis cloc...
Assays: promoter binding affinity calculations on the genome based on PBMs and E...
Files required for reproducibility of computational results. This include Docker file and python packages
Submitter: Uriel Urquiza Garcia
Investigation: Absolute units for proteins in Arabidopsis cloc...
Assays: Python packages
Clock mutants for lhy-1/cca1-11, prr9/7, toc1, lux-4, elf3-1 were transformed with the genomic regions of the associated clock genes tagged with NanoLUC-3FLAG-10His. The tagged genomic constructs were transformed in the mutants using Agrobcterium ABI strain (kindly donated by Prof. Seth Davis University of York). T3 plants resistant to homozygous for BASTA resistance were phenotyped by luciferase imaging asessing period phenotype or plant architecture. Rescuing lines were then used for performing ...
Submitter: Andrew Millar
Investigation: Absolute units for proteins in Arabidopsis cloc...
Assays: Jupyter notebook Predicting Protein Numbers, Protein level time series, TiMet RNA timeseries data
Collection of models used in the introduction of absolute units into A. thaliana circadian clock models, with software resources and documentation. The models are inspired by P2011, published in Pokhilko et al 2012. The study contains Assays that link to the P2011 starting model and the models U2019.1 - .3 and U2020.1 - .3. Each model is shared as a human-readable file in the Antimony language and the associated, machine-readable SBML file, which was automatically generated using the SBML export ...
Submitter: Uriel Urquiza Garcia
Investigation: Absolute units in Arabidopsis clock models up t...
Assays: P2011.1.2, Reproducibility tool set, U2019/U2020 models
The P2011 model (linked in the Assay below) was rescaled to match TiMet RNA data in clock mutants from Flis et al. 2015, also linked here as separate mean and SD files. The raw TiMet data is available elsewhere on FAIRDOMHub.
Submitter: Andrew Millar
Investigation: Absolute units in Arabidopsis clock models up t...
The model is an extensio of PLM_67v3 with an additional an additional variable Temp in ODE 25. This change allows to simulated warm pulses that affect EC stability using COPASI.
Originally submitted to PLaSMo on 2014-03-10 13:16:25
Submitter: BioData SynthSys
Investigation: Urquiza Garcia, Uriel
Model that eliminates several light inputs. RVE8, NOX are incorporated. Individual representation of CCA1 and LHY. Several changes in conections and light inputs. Fogelmark reports eight parameter sets. This SBML file contains the first parameter set Related PublicationsFogelmark K, Troein C (2014). Rethinking transcriptional activation in the Arabidopsis circadian clock.. PLoS Comput Biology. Retrieved from: http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003705Originally ...
Submitter: BioData SynthSys
Investigation: Urquiza Garcia, Uriel
Assays: F2014.1 - PLM_1030, version 1