An existing detailed kinetic model for the steady-state behavior of yeast glycolysis was tested for its ability to simulate dynamic behavior. This model (dupreez2) is an oscillating version of the basis kinetic model (dupreez1) derived from that published by Teusink et al., 2000 (PMID: 10951190).
SEEK ID: https://fairdomhub.org/models/75?version=3
1 item is associated with this Model:- dupreez2.dat (uuencoded file - 10.3 KB)
Organism: Saccharomyces cerevisiae
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Execution or visualisation environment: JWS Online
Model image: No image specified
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David D van Niekerk
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Views: 3897 Downloads: 2
Created: 23rd Jul 2012 at 18:48
Last updated: 23rd Jul 2012 at 23:27
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Version 3 (latest) Created 23rd Jul 2012 at 23:27 by Franco du Preez
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Projects: SysMO DB
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester
Expertise: Glycolysis, Limit cycle oscillations
Tools: Java, Mathematica
Projects: PSYSMO, MOSES, SysMO DB, SysMO-LAB, SulfoSys, SulfoSys - Biotec, Whole body modelling of glucose metabolism in malaria patients, FAIRDOM, Molecular Systems Biology, COMBINE Multicellular Modelling, HOTSOLUTE, Steroid biosynthesis, Yeast glycolytic oscillations, Computational pathway design for biotechnological applications, SCyCode The Autotrophy-Heterotrophy Switch in Cyanobacteria: Coherent Decision-Making at Multiple Regulatory Layers, Project Coordination, WP 3: Drug release kinetics study, Glucose metabolism in cancer cell lines
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester, University of Stellenbosch, University of Manchester - Department of Computer Science, Stellenbosch University
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that:
- facilitates and maximises the potential for data exchange between SysMO research groups;
- maximises the ‘shelf life’ and ...
Programme: SysMO
Public web page: http://www.sysmo-db.org/
Organisms: Not specified
Investigating oscillations at the level of yeast populations and individual cells
Submitter: Katy Wolstencroft
Studies: Detailed kinetics of yeast glycolytic oscillation, Sustained glycolytic oscillations in individual isolated yeast cells
Assays: Detailed kinetic model of yeast glycolytic oscillation, Metabolite concentrations in yeast glycolytic oscillations, Modelling sustained glycolytic oscillations in individual isolated yeast...
Snapshots: No snapshots
Submitter: Katy Wolstencroft
Investigation: Yeast Glycolytic Oscillations
Assays: Detailed kinetic model of yeast glycolytic oscillation, Metabolite concentrations in yeast glycolytic oscillations
Snapshots: No snapshots
Submitter: Katy Wolstencroft
Biological problem addressed: Model Analysis Type
Investigation: Yeast Glycolytic Oscillations
Organisms: Saccharomyces cerevisiae
Models: Detailed kinetic model of yeast glycolytic osci..., Detailed kinetic model of yeast glycolytic osci..., Detailed kinetic model of yeast glycolytic osci..., Detailed kinetic model of yeast glycolytic osci..., Detailed kinetic model of yeast glycolytic osci..., Detailed kinetic model of yeast glycolytic osci..., Detailed kinetic model of yeast glycolytic osci...
SOPs: No SOPs
Data files: Das (1991) NADH and ATP concentrations determin..., Das (1991) Time varying concentrations for meta..., Richard (1996) Concentrations of oscillating gl... and 7 hidden items
Snapshots: No snapshots
Abstract (Expand)
Authors: , David D van Niekerk, Bob Kooi, Johann M Rohwer,
Date Published: 21st Jun 2012
Publication Type: Not specified
PubMed ID: 22712534
Citation:
Abstract (Expand)
Authors: , David D van Niekerk,
Date Published: 13th Jun 2012
Publication Type: Not specified
PubMed ID: 22686585
Citation: