Mathematical modelling of the agr operon in Staphylococcus aureus Version 1
Simulate Model on JWSQuorum sensing(QS) allows the bacteria to monitor their surroundings and the size of their population. Staphylococcus aureus makes use of QS to regulate the production of virulence factors. This mathematical model of the QS system in S aureus was presented and analyzed (Journal of Mathematical Biology(2010) 61:17–54) in order to clarify the roles of the distinct interactions that make up the QS process, demonstrating which reactions dominate the behaviour of the system at various timepoints.
Simulation link for JWS Online: http://jjj.mib.ac.uk/webMathematica/Examples/run.jsp?modelName=jabbari2
SEEK ID: https://fairdomhub.org/models/60?version=1
1 item is associated with this Model:-
jabbari2.dat (uuencoded file - 2.63 KB)
Organism: Not specified
Model type: Ordinary differential equations (ODE)
Model format: Not specified
Execution or visualisation environment: JWS Online
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Additional credit
Adrian Koerber, Paul Williams
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Views: 4341 Downloads: 177 Runs: 0
Created: 12th Oct 2011 at 12:26
Last updated: 7th Mar 2012 at 12:53
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Version 1 (earliest) Created 12th Oct 2011 at 12:26 by Franco du Preez
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Projects: SysMO DB
Institutions: Manchester Centre for Integrative Systems Biology, University of Manchester
Projects: COSMIC
Institutions: University of Nottingham
I am a Birmingham and MRC Fellow in mathematical biology. Specialising in the modelling of gene regulation networks using both numerical and analytical approaches, my work spans a range of biological applications, from drug development to bioenergy to understanding bacterial behaviour. My MRC fellowship gave me the opportunity to gain experimental training in order to generate the complementary data required to adopt a truly interdisciplinary approach to mathematical modelling in biology.
I worked ...
Projects: COSMIC
Institutions: University of Nottingham
I am a mathematical modeller concerned primarily with applications in biology,
SysMO is a European transnational funding and research initiative on "Systems Biology of Microorganisms".
The goal pursued by SysMO was to record and describe the dynamic molecular processes going on in unicellular microorganisms in a comprehensive way and to present these processes in the form of computerized mathematical models.
Systems biology will raise biomedical and biotechnological research to a new quality level and contribute markedly to progress in understanding. Pooling European research ...
Projects: BaCell-SysMO, COSMIC, SUMO, KOSMOBAC, SysMO-LAB, PSYSMO, SCaRAB, MOSES, TRANSLUCENT, STREAM, SulfoSys, SysMO DB, SysMO Funders, SilicoTryp, Noisy-Strep
Web page: http://sysmo.net/
The main objectives of SysMO-DB are to: facilitate the web-based exchange of data between research groups within- and inter- consortia, and to provide an integrated platform for the dissemination of the results of the SysMO projects to the scientific community. We aim to devise a progressive and scalable solution to the data management needs of the SysMO initiative, that:
- facilitates and maximises the potential for data exchange between SysMO research groups;
- maximises the ‘shelf life’ and ...
Programme: SysMO
Public web page: http://www.sysmo-db.org/
Abstract (Expand)
Authors: , , Adrian J Koerber, Paul Williams
Date Published: 19th Feb 2009
Publication Type: Not specified
