Mathematical modelling of the sporulation-initiation network in Bacillus subtilis.
Version 1

An ODE model of the gene regulation network governing sporulation initiation in Bacillus subtilis to be run in Matlab.

The network incorporates four sporulation-related signals: nutrient supply, DNA damage, the products of the competence genes and the bacterial population size.

Run execute_bacillus_sporulation_initiation.m to simulate the model. This file also contains the signal-related parameters which can be altered to investigate the effect of competing signals.

Some results for this model are published in Jabbari, Heap & King, 2010, Mathematical modelling of the sporulation-initiation network in Bacillus subtilis revealing the dual role of the putative quorum-sensing signal molecule PhrA, Bulletin of Mathematical Biology (uploaded into the publications section of SEEK).

SEEK ID: https://fairdomhub.org/models/33?version=1

1 item is associated with this Model:
  • bacillus_sporulation_initiation.tar (Tar archive - 20 KB) Download

Organism: Bacillus subtilis

Model type: Ordinary differential equations (ODE)

Model format: Matlab package

Execution or visualisation environment: Not specified

Model image: No image specified

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Views: 3607   Downloads: 139

Created: 4th Jun 2010 at 13:35

Last updated: 16th Jul 2014 at 14:39

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Version 1 (earliest) Created 4th Jun 2010 at 13:35 by Sara Jabbari

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