Projects: COVID-19 Disease Map
Institutions: Ontario Institute for Cancer Research

Expertise: Software Engineering, Bioinformatics, Biocuration
Projects: COVID-19 Disease Map
Institutions: Ontario Institute for Cancer Research

Expertise: Molecular Biology, Bioinformatics, Biocuration
Tools: Reactome
- automated integration of transcriptomic and reactome data to differential equations
- structure of the paths is maintained
- continuous fermentation model in standard format for data integration, two component model (cell and fermenter)
call >> Kegg2SBToolbox2('model_map.txt', 'reactions_compounds_final.csv','extracellular.txt','testmodel.txt') for an example
where
model_map is the desired mapping of species,
reaction_compounds_final.csv is the entire network,
extracellular.txt is a manual
...
Creator: Sebastian Curth
Submitter: Sebastian Curth
Investigations: Modular Model Building
Studies: Automated Model Building
RCM: Reaction-Compound Mapping, an edge between nodes means reaction contains metabolite
MMM: Metabolite-Metabolite Mapping, an edge between nodes means these metabolites are reaction partners
_comp: entire network after removal of duplicated edges
_del: taken from the entire network the largest connected subgraph after deletion of a set of nodes
_upload: entire network before removal of duplicated edges
X_depthY: subgraphs where X is a chosen central component and Y is the Yth of neighbour to
...
Creator: Sebastian Curth
Submitter: Sebastian Curth
Investigations: Modular Model Building
Studies: Reactome Analysis
Assays: Graph Analysis, KEGG Data Mining
Columnwise datamatrix of reactions, gene identifiers, substrates and products. The direction of reactions is not given.
Creator: Sebastian Curth
Submitter: Sebastian Curth