The major theme of the research in my laboratory is bacterial gene regulation. We are interested in signal perception mechanisms (in particular oxygen); signal transduction (ligand induced protein confromational changes); interaction of transcription factors with the core transcription machinery; interactions between transcription factors to integrate multiple signals; and the influence of promoter architectures on these events. We are also interested in aome aspects of post-transcriptional ...
Expertise: Microbiology, Biochemistry, Molecular Biology, Escherichia coli physiology, Bacterial Cell Biology, Regulatory Networks, Molecular microbiology, Cellular biology of metals
Tools: Microarray analysis, Molecular biology techniques (RNA/DNA/Protein), qRT-PCR, RNA / DNA Techniques, bacterial chemostat culture, Mutant and Strain Construction
Post-doctoral research associate working in Sheffield in the SUMO consortium.
I am a first year PhD student, working with Professor Robert Poole (University of Sheffield), Professor Jeff Green (University of Sheffield) and Dr Jamie Wood (University of York) using a systems biology approach to study respiration in Escherichia coli.