Investigations

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Kinetic understanding of the T. brucei trypanothione synthesis pathway

SilicoTryp

Aim. To provide critical quantitative parameter information and to model redox balance by determining the cellular concentration of all enzymes involved in the trypanothione-dependent hydroperoxide detoxification system of trypanosomes and by performing the kinetic characterization of the involved enzymes under pseudo-physiological conditions.

Submitter: Alejandro Leroux

Studies: Determination of the redox state and the total concentration of the tryp..., Kinetic characterization of trypanothione-dependent enzymes, Kinetic modelling of Trypanothione Synthetase to elucidate the enzyme me...

Assays: Creating kinetic model of Trypanothione Synthetase, Trypanothione synthetase ATP consumption steady state data, Trypanothione synthetase Gsp and T(SH)2 production measured by HPLC

Snapshots: No snapshots

Created: 18th Jun 2012 at 15:32, Last updated: 31st Jul 2014 at 08:10

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