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Robust IgM responses following intravenous vaccination with Bacille Calmette-Guerin associate with prevention of Mycobacterium tuberculosis infection in macaques. Irvine et al (2021)

Hi-IMPAcTB

Development of an effective tuberculosis (TB) vaccine has suffered from an incomplete understanding of the correlates of protection against Mycobacterium tuberculosis (Mtb). Intravenous (i.v.) vaccination with Bacille Calmette–Guérin (BCG) provides nearly complete protection against TB in rhesus macaques, but the antibody response it elicits remains incompletely defined. Here we show that i.v. BCG drives superior antibody responses in the plasma and the lungs of rhesus macaques compared to ...

Submitter: Dikshant Pradhan

Investigation: IMPAcTB

Assays: Anti-Microbial Assay – Metadata, Functional Assay – Metadata, Luminex Assay – Metadata, Luminex Data Processing – Data Attached, NHP Tissue Collection – Metadata

Snapshots: Snapshot 1

Created: 25th Oct 2021 at 00:43, Last updated: 2nd Sep 2022 at 17:03

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