Assays

We here create a kinetic model for a single enzyme within the T. brucei trypanothione synthesis pathway, the enzyme trypanothione synthetase based on the insights from the laboratory experiments

Submitter: Jurgen Haanstra

Biological problem addressed: Enzymology

Investigation: Kinetic understanding of the T. brucei trypanot...

Study: Kinetic modelling of Trypanothione Synthetase t...

Organisms: No organisms

Models: Final model of TryS

SOPs: No SOPs

Data files: Activity of TbTryS measured by HPLC, Activity of TbTryS under different substrate/pr..., TryS: entire dataset with simulations, TryS: extended model description

Snapshots: No snapshots

Created: 31st Jul 2014 at 08:26, Last updated: 8th Nov 2017 at 14:21

Modelling the gene expression cascade with length-dependent processes

SilicoTryp

The RNAseq data on mRNA processing and mRNA decay were used to update a previously published model and to interrogate which process should be dependent on mRNA length

Submitter: Jurgen Haanstra

Biological problem addressed: Model Analysis Type

Investigation: Gene expression in Trypanosoma brucei

Study: Determination and integration of abundance, pro...

Organisms: No organisms

Models: No Models

SOPs: No SOPs

Data files: mRNA decay, mRNA half-lives, precursor mRNA half-lives

Snapshots: No snapshots

Created: 31st Jul 2014 at 08:47, Last updated: 8th Nov 2017 at 14:21

Assays

Filters ×

Filters