Francisco Pinto

This project aims to characterise the mechanisms through which microRNAs and small non-coding RNAs act to regulate cellular processes focusing on Naïve CD4 T cell activation and viral replication - namely HIV - and to explore their potential use as a therapeutic co-adjuvant agents or targets.

Understanding the molecular basis of diseases can shed light into new methods to manage and cure diseases. Exploring the common or unique molecular mechanisms among a group of diseases may enhance our understanding of each disease or uncover therapeutic approaches that can be effective in multiple diseases. In this project we develop methods that use biological networks and known gene-disease associations to identify common molecular mechanisms associated across multiple diseases.