Studies

2 Studies visible to you, out of a total of 2

Core model predicting combined mutations and perturbations

MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine

Predictions made using the core model for combinatorial perturbations to the model simulating combined effects from OE, KO mutants, perturbations and time series concentrations.

Submitter: Niels Zondervan

Investigation: Modelling of M. pneumoniae metabolism

Assays: 40 samples, OE mutants of glycolysis and pyruvate metabolism enzymes com...

Snapshots: No snapshots

Created: 1st May 2017 at 10:18, Last updated: 20th Nov 2019 at 23:19

Core Model predictions

MycoSynVac - Engineering Mycoplasma pneumoniae as a broad-spectrum animal vaccine

Validation of the core model of glycolysis, pyruvate metabolism and ATPase reaction using OE, KO mutant samples and perturbation samples

Submitter: Niels Zondervan

Investigation: Modelling of M. pneumoniae metabolism

Assays: Dynamic model simmulation pipeline, Metabolic control analysis (local and global), Validation by simulating independent mutant and perturbation samples

Snapshots: No snapshots

Created: 19th Apr 2017 at 07:57, Last updated: 20th Nov 2019 at 23:19

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