Miguel Ponce-de-Leon
SEEK ID: https://fairdomhub.org/people/1536
Location:
Spain
ORCID:
https://orcid.org/0000-0002-7496-844X
Joined: 3rd Apr 2020
Expertise: Not specified
Tools: Not specified
Their tagsRelated items
The Disease Maps Project is designed as a large-scale community effort. It is a network of groups that work together in order to better understand disease mechanisms. The project exchanges best practices, share information, develop tools to make it easier for all the involved groups to achieve their goals.
Projects: COVID-19 Disease Map
Web page: https://disease-maps.org
Here we share resources and best practices to develop a disease map for COVID-19. The project is progressing as a broad community-driven effort. We aim to establish a knowledge repository on virus-host interaction mechanisms specific to the SARS-CoV-2. The COVID-19 Disease Map is an assembly of molecular interaction diagrams established based on literature evidence.
Programme: Disease Maps
Public web page: http://doi.org/10.17881/covid19-disease-map
Multiscale and multicellular simulation of SARS-CoV-2 infection uncover points of intervention to evade apoptosis.
Summary:
Our framework enables the simulation of the dynamics of signaling pathways that include the relevant players in SARS-CoV-2 infection, at the level of the individual cell and of the cell population. These different players encompass the virus, epithelial and immune cells. The model focuses on apoptosis and suggests two knock out alterations that force apoptosis of the ...
Interactions of Nsp4 and Nsp6 proteins of SARS-CoV-2.
Creators: Arnau Montagud, Miguel Ponce-de-Leon
Submitter: Marek Ostaszewski
Model type: Graphical model
Model format: SBML
Environment: Not specified
External Link