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Hepatic ChREBP orchestrates intrahepatic carbohydrate metabolism to limit hepatic glucose 6-phosphate and glycogen accumulation in a mouse model for acute Glycogen Storage Disease type Ib

PoLiMeR - Polymers in the Liver: Metabolism and Regulation

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Abstract (Expand)

Carbohydrate Response Element Binding Protein (ChREBP) is a glucose 6-phosphate (G6P)-sensitive transcription factor that acts as a metabolic switch to maintain intracellular glucose and phosphate …

Authors: K.A. Krishnamurthy, M.G.S. Rutten, J.A. Hoogerland, T.H. van Dijk, T. Bos, M. Koehorst, M.P. de Vries, N.J. Kloosterhuis, H. Havinga, B.V. Schomakers, M. van Weeghel, J.C. Wolters, B.M. Bakker, M.H. Oosterveer

Date Published: 2024

Publication Type: Journal

DOI: 10.1016/j.molmet.2023.101838

Citation: Molecular Metabolism 79:101838

Created: 22nd Feb 2024 at 11:31, Last updated: 22nd Feb 2024 at 11:58

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