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Steroid biosynthesis4
Submitter
Jacky Snoep4
Creator
Jacky Snoep4
4
Studies visible to you, out of a total of 4
HSD11B1 was inhibited in human subcutaneous and omental adipose tissue, and the effect on oxygenated adrogen metabolism was studied.
Surface plots showing the computational analysis of combined HSD11B1/AKR1C3 ratios and HSD11B1 inhibition.
Submitter: Jacky Snoep
Investigation: Effect of 11BHSD inhibition on 11-ketotestoster...
Assays: Model for computational analysis of HSD11B1/AKR1C3 ratio variation and H...
HSD11B1 was inhibited by CBX and the effect of the inhibition on Cortisone and 11KA4 conversion by HSD11B1/AKR1C3 incubations were measured.
HSD11B1 and AKR1C3 transfected cells were mixed at difefrent ratios and effects on cortisone conversion (Fig. 2B) and 11KT production (Fig. 2C) were measured and simulated.
